CBD-DMH

CBD-DMH
识别信息
	IUPAC命名法 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol; ;
CAS号	97452-63-6（(−)-enantiomer）
PubChem CID	126670;
ChemSpider	112525;
UNII	P28FSD6QS7;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID10913915 ;
化学信息
化学式	C25H38O2
摩尔质量	370.57
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CCCCCCC(C)(C)c1cc(c(c(c1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O;
	InChI InChI=1S/C25H38O2/c1-7-8-9-10-13-25(5,6)19-15-22(26)24(23(27)16-19)21-14-18(4)11-12-20(21)17(2)3/h14-16,20-21,26-27H,2,7-13H2,1,3-6H3/t20-,21+/m0/s1; Key:MPJURNPNPDQYSY-LEWJYISDSA-N;

CBD-DMH（大麻二酚-二甲基庚基，英語：Cannabidiol-dimethylheptyl，也缩写为DMH-CBD），分子式C₂₅H₃₈O₂，是一种人工合成的大麻素，可看做大麻二酚的同系物，其侧链上的戊基被替换成二甲基庚基。^[1]^[2]^[3]^[4]

参考文献

^ Leite JR, Carlini EA, Lander N, Mechoulam R. Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs. Pharmacology. 1982, 24 (3): 141–6. PMID 7071126. doi:10.1159/000137588.
^ Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. British Journal of Pharmacology. October 2001, 134 (4): 845–52. PMC 1573017 . PMID 11606325. doi:10.1038/sj.bjp.0704327.
^ Ben-Shabat S, Hanus LO, Katzavian G, Gallily R. New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity. Journal of Medicinal Chemistry. February 2006, 49 (3): 1113–7. PMID 16451075. doi:10.1021/jm050709m.
^ Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z. Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells. Journal of Basic and Clinical Physiology and Pharmacology. May 2016, 27 (3): 289–96. PMID 26540221. doi:10.1515/jbcpp-2015-0071 .

识别信息

IUPAC命名法 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol
CAS号	97452-63-6（(−)-enantiomer） ^Y
PubChem CID	126670
ChemSpider	112525
UNII	P28FSD6QS7
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID10913915
化学信息
化学式	C₂₅H₃₈O₂
摩尔质量	370.57
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES CCCCCCC(C)(C)c1cc(c(c(c1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O
InChI InChI=1S/C25H38O2/c1-7-8-9-10-13-25(5,6)19-15-22(26)24(23(27)16-19)21-14-18(4)11-12-20(21)17(2)3/h14-16,20-21,26-27H,2,7-13H2,1,3-6H3/t20-,21+/m0/s1 Key:MPJURNPNPDQYSY-LEWJYISDSA-N