The city of Cambridge is located in Middlesex County, Massachusetts, and it is a significant suburb of Boston. Cambridge is also a component of the greater Boston metropolitan region. The population of the city was recorded as 118,403 during the time period covered by the United States Census in the year 2020. This placed it as the fourth most populated city in the state, falling behind Boston, Worcester, and Springfield. Despite the fact that the county government was eliminated in 1997, it is still considered to be one of the two de jure county seats of Middlesex County. It was called in honour of the University of Cambridge in England, which was formerly also an important centre of the Puritan religion accepted by the town's founders. Cambridge is located just north of Boston, across the Charles River, and it was named in honour of the university.
In addition to Radcliffe College, which was absorbed into Harvard University in the 19th century, Harvard University, the Massachusetts Institute of Technology (MIT), Lesley University, and Hult International Business School are also located in Cambridge. Because of the high number of successful companies that have formed in the area around Kendall Square in Cambridge since 2010, the square has been given the nickname "the most inventive square mile on the world."