Open Pathology Project

Open Pathology Education Project aims at providing open pathology educational resources for students and educators. This project involves developing, curating and sharing pathology related educational material under CC licenses. Here is the list of topics under the scope of this project. This page contains 87 topic areas.

Image	Article	Description	Commons histopathology category	Structured data item
	Neutrophils	Micrograph showing neutrophils in acute inflammation.	Category: Neutrophils	Neutrophil
	Plasma cells	Plasma cell showing eccentrically placed round nucleus with cart wheel like chromatin.	Category: Plasma cells	Plasma cell
	Eosinophils	Micrograph showing low power view of Eosinophils.	Category: Eosinophils	Eosinophil
	Lymphocyte	Micrograph showing lymphocytes in caseating granuloma.	Category: Lymphocytes	Lymphocyte
	Fibroblasts	Fibroblasts in intestinal pneumonia	Category: Fibroblasts	Fibroblast
	Foam cells	Histopathology of cholesterolosis of the gallbladder, with annotated foam cell	Category: Foam cell	Foam cell
	Macrophages	Lung showing congestion with plenty of alveolar macrophages containing phagocytosed brownish granular hemosiderin pigment.	Category: Macrophages	Macrophage
	Langhans cells	Langhans giant cell in the centre of a non-caseating granuloma.	Category: Langhans giant cells	Langhans giant cell
	Foreign body giant cells	Micrograph showing a foreign body engulfed by a giant cell.	Category: Foreign body giant cell	Foreign body giant cell
	Granulation tissue	Micrograph showing proliferating capillaries, fibroblasts and acute inflammatory cells.	Category: Histopathology of granulation tissue	Granulation tissue
	Foreign body granuloma	Granulomatous reaction to keratin characterized by foreign body giant cells and chronic inflammatory cells.	Category: Histopathology of foreign body granuloma	Foreign body granuloma, silicone granuloma
	Tuberculous granuloma	Caseating granulomatous lesion with areas of amorphous granular eosinophilic necrotic debris known as caseation (on the right half) bordered by collections of epitheloid cells, Langhan giant cells and lymphocytes.	Category: Histopathology of tuberculous granuloma	Tuberculous granuloma
	Fat necrosis	Breast lump showing an area of fat necrosis showing shadowy outlines of necrotic adipocytes surrounded by an inflammatory reaction with cholesterol clefts.	Category: Histopathology of liponecrosis	Liponecrosis
	Calcinosis cutis	Multiple amorphous basophilic calcium deposits in the dermis.	Category: Histopathology of calcinosis cutis	Calcinosis cutis
	Hemochromatosis liver	Micrograph of hemochromatosis liver showing hepatocytes with coarse golden yellow granules of hemosiderin within the cytoplasm. These granules stain with Prussian blue stain.	Category: Histopathology of hemochromatosis	hereditary hemochromatosis
	Caseous necrosis	Caseating granulomatous lesion with areas of amorphous granular eosinophilic necrotic debris known as caseation (on the right half) bordered by collections of epitheloid cells, Langhan giant cells and lymphocytes.	Category: Histopathology of caseous necrosis	caseous necrosis
	Fatty change in liver	Hepatic parenchymal cell cytoplasm containing clear vacuoles containing fat of varying sizes, displacing the nucleus towards the periphery.	Category: Lipid steatosis	steatosis
	Carcinoma in situ	CIN-III (HSIL) showing diffuse severe atypia with loss of maturation involving full thickness of epithelium with intact basement membrane.	Category: Histopathology of carcinomas in situ	Carcinoma in-situ
	Lymph node metastasis	Lymph node showing metastases from colorectal carcinoma	Category: Lymph node metastases	Lymph node metastasis
	Fibroadenoma	A well circumscribed lesion showing proliferation of intralobular stroma compressing and distorting the epithelium.	Category: Histopathology of breat fibroadenomas	Fibroadenoma
	Tumor giant cell	Malignant neoplasm showing marked anaplasia. Note the marked nuclear pleomorphism, bizarre cells and tumor giant cells.	Category: Histopathology of giant cell tumors	Giant cell tumor
	Capillary hemangioma	Micrograph showing capillary hemangioma of skin.	Category: Histopathology of capillary hemangioma	Capillary hemangioma
	Lepromatous leprosy	Skin biopsy showing epidermal atrophy and multiple dermal infiltrates.	Category: Histopathology of leprosy	Leprosy
	Tuberculoid leprosy	Skin biopsy showing multiple peri-appendageal granulomas.	Category: Histopathology of leprosy	Leprosy
	Tuberculous lymphadenitis	Caseating granulomatous lesion with areas of amorphous granular eosinophilic necrotic debris known as caseation (on the right half) bordered by collections of epitheloid cells, Langhan giant cells and lymphocytes.	Category: Histopathology of tuberculous lymphadenitis	Tuberculous lymphadentis
	Tuberculosis of intestine	The lamina propria is stuffed with wall-to-wall histiocytes. This Kinyoun carbolfuchsin stain shows innumerable acid-fast bacilli	Category: Histopatology of gastrointestinal tuberculosis	Gastrointestinal tuberculosis
	Helminth in appendix	Micrograph showing lumen of appendix and cut section of pin worm.	Category: Histopathology of appendix with Enterobius vermicularis	Parasitic helminthiasis infectious disease
	Chromoblastomycosis	Micrograph of chromoblastomycosis showing sclerotic bodies in dermis.	Category: Histopathology of chromoblastomycosis	Chromoblastomycosis
	Amoebiasis	Colonic biopsy showing trophozoite of Entamoeba Histolytica with ingested red blood cells.	Category: Histopathology of amoebiasis	Amoebiasis
	Rhinosporidiosis	Section of a polyp containing Rhinosporidium seeberi	Category: Histopathology of rhinosporidiosis	Rhinosporidiosis
	Filarial lymphadenitis	Micrograph showing section of an adult filarial worm. Surrounding tissue shows dense infiltration of eosinophils.	Category: Histopathology of filariases	filariasis
	Reactive hyperplasia of lymph node	Histopathology of a reactive lymph node by the cystic duct in a case of cholecystitis.	Category: Reactive hyperplasia of lymph node	Reactive hyperplasia
	Diffuse B-cell lymphoma	Lymph node FNA specimen showing diffuse large B cell lymphoma.	Category: Histopathology of diffuse large B cell lymphoma	Diffuse large B-cell lymphoma
	Follicular lymphoma	Micrograph showing a small B-cell lymphoma compatible with follicular lymphoma. H&E stain.	Category: Histopathology of follicular lymphoma	Follicular lymphoma
	Hodgkin's lymphoma	Micrograph of a lymph node in Hodgkin's lymphoma with the characteristic Reed-Sternberg cell. RS cell is a large cell with abundant amophophilic cytoplasm and binucleate mirror image nuclei. Each nucleus contains an acidophilic nucleolus surrounded by a halo.	Category: Histopathology of Hodgkin's lymphoma	Hodgkin's lymphoma
	Congestive hepatopathy (CVC liver)	Micrograph showing chronic venous congestion of liver	Category: Histopathology of chronic venous congestion of liver	Congestive hepatopathy of liver
	Chronic venous congestion of spleen	Micrograph showing chronic venous congestion of spleen. Sinusoids are dialated. Organized foci of old hemorrhage seen as areas of fibrosis containing brown pigment (hemosiderin).	Category: Histopathology of chronic venous congestion of spleen	Chronic venous congestion of spleen
	Cavernous hemangioma	Histopathological image reprsenting a cavernous hemangioma of the liver.	Category: Histopathology of cavernous liver hemangioma	Cavernous hemangioma
	Atherosclerosis	Atherosclerosis showing extracellular lipid accumulation and foam cells.	Category: Histopathology of atherosclerosis	Atherosclerosis
	Emphysema	Micrograph of empysema lung showing dialated, large alveoli separated by thin septa. Some septae are ruptured and appear to be floating in the alveloar spaces. Grossly emphysematous lung appears pale and voluminous.	Category: Histopathology of pulmonary emphysema	Emphysema
	Squamous cell carcinoma of lung	Micrograph of squamous Cell Carcinoma Lung. A lobule of polygonal squamous cells with moderate amount of eosinophilic cytoplasm and hyperchromatic nuclei are seen. The islands show abnormal keratinization in the form of epithelial pearls in the centre. These epithelial pearls are whorls or eddies of malignant cells with pink keratin in the centre.	Category: Histopathology of squamous cell carcinoma of the lung	Squamous cell carcinoma of lung
	Bronchoalveolar carcinoma	Lepidic pattern of growth of tumor cells along the alveolar wall resembling butterfly sitting on fence. Normal alveoli is seen towards right side.	Category: Histopathology of bronchio-alveolar carcinoma	Bronchio-alveolar carcinoma
	Pulmonary tuberculosis	Pulmonary tuberculosis characterized by granulomatous inflammation with necrotizing epithelioid granulomas.	Category: Histopathology of pulmonary tuberculosis	Pulmonary tuberculosis
	Aspergilloma	This ectatic bronchus is filled with a colony of Aspergillus. The organisms are confined to the lumen of the bronchus and do not invade surrounding tissues.	Category: Histopathology of pulmonary aspergilloma	Aspergilloma
	Small cell carcinoma of lung	Micograph of small Cell Carcinoma Lung. The tumor appears blue because the malignant epithelial cells are small with scanty cytoplasm, nuclei shows finely granulated chromatin. Cells are seen in clusters. There is nuclear overlapping with moulding and crushing.	Category: Histopathology of small cell lung cancer	Small cell lung cancer
	Pneumonia	Lung tissue showing numerous neutrophils with minimal exudates in the alveolar space with septal wall congestion.	Category: Histopathology of pneumonia	Lobar pneumonia
	Aspiration pneumonia	Lung tissue where alveoli contain hemosiderin-laden macrophages and occasional multinucleate giant cells as well as red blood cells.	Category: Histopathology of aspiration pneumonia	Aspiration pneumonia
	Adenocarcinoma colon	Micrograph of carcinoma colon showing malignant glands.Nuclei are small and vesicular, located at the bottom of the cell. The cells show increased nucleocytoplasmic ratio.	Category: Histopathology of colorectal adenocarcinoma	Colorectal carcinoma
	Chronic gastric ulcer	Acute stress ulcer of stomach in erosive gastritis.	Category: Histopathology of gastritis	Gastritis
	Adenocarcinoma stomach	Micrograph of carcinoma stomach. The glands are seen infiltrating the muscle layer. The neoplastic cells are arranged in cords and in glandular pattern. The cells show dysplastic features. Signet rings with nucleus pushed to the periphery are seen in some types of adenocarcinoma.	Category: Histopathology of adenocarcinoma stomach	Adenocarcinoma of stomach
	Squamous cell carcinoma of the skin	Well-differentiated squamous cell carcinoma skin showing malignant cells with mild atypia resembling normal squamous epithelial cells with intercellular bridges, individual cell keratinisation and nests of keratin pearls.	Category: Histopathology of squamous cell carcinoma of the skin	Squamous cell carcinoma
	Pleomorphic adenoma	Micrograph of Pleomorphic Adenoma of Salivary gland. The section shows a cellular area interspersed with islands of lighter stained bluish myxoid tissue. The cellular area is the epithelial element and is composed of cells arranged in sheets and trabeculae. The myxoid areas may resemble cartilage and represent the mesenchymal element.	Category: Histopathology of pleomorphic adenoma	Pleomorphic adenoma
	Cirrhosis	Micrograph of liver showing nodules of parenchymal liver cells engulfed by broad bands of fibrous tissue. The liver has lost its normal architecture.	Category: Histopathology of alcoholic cirrhosis	Liver cirrhosis
	Fatty liver	Hepatic parenchymal cell cytoplasm containing clear vacuoles containing fat of varying sizes, displacing the nucleus towards the periphery.	Category: Lipid steatosis	steatosis
	Serous cystadenoma	Histopathology of serous cystadenoma, with admixed scattered ciliated cells. This case closely resembles normal surface endometrial epithelium of the uterus	Category: Histopathology of ovarian serous cystadenoma	Ovarian cystadenoma
	Mucinous cystadenoma	Micrograph showing Mucinous Cystadenoma of ovary. The cyst wall is lined by tall columnar epithelium and filled with mucin.	Category: Histopathology of mucinous cystadenoma	Mucinous cystadenoma
	Dysgerminoma	Dysgerminoma characterized by uniform cells resembling primordial germ cells separated by fibrous septa with lymphocytes.	Category: Histopathology of ovarian dysgerminoma	Ovarian dysgerminoma
	Vesicular mole	Micrograph of vesicular mole showing oedematous chorionic villus with circumferential proliferation of trophoblasts.	Category: Histopathology of chorionic villi	chorionic villi
	Products of gestation	Micrograph showing products of conception. Chorionic villi and decidual tissue are seen.	Category: Histopathology of products of conception	products of conception
	Benign cystic teratoma	Micrograph of Teratoma Ovary showing areas of cartilage, mucous glands, squamous epithelium and hair follicle.	Category: Histopathology of mature teratoma of ovary	teratoma
	Seminoma testis	Micrograph of seminoma testes showing lobules of uniform cells separated by delicate septae of fibrous tissue. These cells can have a distinct outline with clear cytoplasm. The nuclei are large, with central prominent nucleolus.	Category: Histopathology of testicular seminoma	seminoma
	Endometrium	Micrograph showing proliferative phase of endometrium.	Category: Histology of endometrium	endometrium
	Leiomyoma uterus	Micrograph of leiomyoma uterus showing bundles of smooth muscle cells of uniform size and shape. The cells are spindle shaped with oval nucleus.	Category: Histopathology of uterine fibroids	Leiomyoma
	Squamous cell carcinoma of cervix	Invasive Squamous Carcinoma of the Cervix. Cold Knife Cone.	Category: Histopathology of squamous cell carcinoma of the cervix	Invasive squamous carcinoma of cervix
	Cystic hyperplasia of endometrium	Micrograph showing cystic hyperplasia of endometrium. Cystically dialated glands are lined by proliferative type of epithelium. Stroma also resembles proliferative phase. No atypia is seen in the cells.	Category: Histopathology of hyperplasia endometrium	Cystic hyperplasia
	Neuroblastoma	Histopathology specimen of neuroblastoma showing Homer Wright rosettes (HE stain)	Category: Histopathology of neuroblastoma	Neuroblastoma
	Nephroblastoma	Adult Wilm's tumor showing tubular pattern resembling pseudo-rosettes at places.	Category: Histopathology of Wilm's tumor	Wilm's tumor
	Retinoblastoma	This retinoblastoma has characteristic Flexner-Wintersteiner rosettes with circular alignment of short columnar cells around a central lumen.	Category: Histopathology of retinoblastoma	Retinoblastoma
	Osteoclastoma	The micrographs show the characteristic giant cells with nuclei that have a similar appearance to the surrounding (mononuclear) cells.	Category: Histopathology of giant cell tumor of bone	Giant cell tumor
	Osteosarcoma	Small cell osteosarcoma, like other osteosarcomas has osteoid, the extracellular organic component of bone. On H&E stained sections, osteoid has a pink, homogeneous appearance and surrounds osteoblasts or osteosarcoma cells.	Category: Histopathology of osteosarcoma	Osteosarcoma
	Plasmacytoma	Plasma cell showing eccentrically placed round nucleus with cart wheel like chromatin.	Category: Histopathology of plasmacytoma	Plasmacytoma
	Osteochondroma	Perichondrium covering the cartilage cap, which merged into the underlying spongiosa.	Category: Histopathology of osteochondroma	osteochondroma
	Hashimoto's thyroiditis	Hashimoto's thyroiditis with lymphoid infiltration.	Category: Hashimoto's thyroiditis with lymphoid infiltration	Hashimoto's thyroiditis
	Papillary carcinoma thyroid	The phenomenon of orphan Anne eyes in papillary thyroid cancer.	Category: Histopathology of thyroid papillary carcinoma	papillary carcinoma
	Nodular colloid goitre	Histopathology of multinodular toxic goiter, showing normal thyroid follicles with calcification but no psammoma bodies in low magnification and no atypia in higher magnification.	Category: Histopathology of goitres	goiter
	Glioblastoma	Biopsy specimen of a Glioblastoma showing extensive cell pleomorphism	Category: Histopathology of glioblastoma	glioblastoma
	Meningoma	Concentrically calcified basophilic structure in the centre of the field in a meningioma.	Category: Histopathology of meningoma	meningoma
	Fibrocystic disease of breast	Intermediate magnification micrograph of fibrocystic change of the breast with apocrine metaplasia.	Category: Histopathology of fibrocystic breast changes	fibrocystic breast
	Infiltrative ductal carcinoma	Atypical cells with moderate amount of eosinophilic cytoplasm and round to oval dark nucleus with moderate pleomorphism (Papanicolaou, 400X)	Category: Histopathology of invasive carcinoma of no special type	invasive breast carcinoma
	Fibroadenoma	A well circumscribed lesion showing proliferation of intralobular stroma compressing and distorting the epithelium.	Category: Histopathology of breast fibroadenomas	fibroadenoma
	Phyllodes tumor	Photomicrograph of a malignant phyllodes tumour. Note stromal cellularity and mitotic figures.	Category: Histopathology of cystosarcoma phyllodes	Phyllodes tumor
	Lipoma	Micrograph of a lipoma showing fat cells.	Category: Histopathology of lipomas	Lipoma
	Basal cell carcinoma	Surgical excision biopsy specimen showing histopathology of basal cell carcinoma.	Category: Histopathology of basal cell carcinoma	Basal cell carcinoma
	Malignant melanoma	Malignant spindle cell neoplasm, showing numerous mitotic figures, including atypical tripolar mitotic figure, in the centre.	Category: Histopathology of melanoma	Malignant melanoma
	Squamous papilloma	Micrograph showing squamous cell papilloma of the tongue.	Category: Histopathology of squamous cell carcinoma	Squamous papilloma
	Renal cell carcinoma	Micrograph of clear cell renal cell carcinoma showing cells with clear cytoplasm, typically arranged in nests and nuclear atypia.	Category: Histopathology of renal cell carcinoma	Renal cell carcinoma
	Cresenteric glomerulonephritis	Photomicrograph of the renal biopsy showing prominent fibrocellular crescent formation and moderate mesangial proliferation in a glomerulus.	Category: Histopathology of glomerulonephritis	glomerulonephritis
	Transitional cell carcinoma	Histopathology of transitional carcinoma of the urinary bladder.	Category: Histopathology of transitional cell carcinoma	Urothelial carcinoma

Histopathology images on Wikimedia Commons belonging to the above disease conditions have now been tagged with structured data. You can access these images by querying on Commons SPARQL query service. The query service has a backlog of about two months, so newly added structured data are cannot be queried using this service.