| methylumbelliferyl-acetate deacetylase |
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| Identifiers |
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| EC number | 3.1.1.56 |
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| CAS number | 83380-83-0 |
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| Databases |
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| IntEnz | IntEnz view |
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| BRENDA | BRENDA entry |
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| ExPASy | NiceZyme view |
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| KEGG | KEGG entry |
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| MetaCyc | metabolic pathway |
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| PRIAM | profile |
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| PDB structures | RCSB PDB PDBe PDBsum |
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| Gene Ontology | AmiGO / QuickGO |
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| Search |
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| PMC | articles |
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| PubMed | articles |
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| NCBI | proteins |
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The enzyme methylumbelliferyl-acetate deacetylase (EC 3.1.1.56, esterase D) catalyzes the reaction
- 4-methylumbelliferyl acetate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 4-methylumbelliferone + acetate
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 4-methylumbelliferyl-acetate acylhydrolase. This enzyme is also called esterase D.
References
- "Esterase D: a new human polymorphism". Ann. Hum. Genet. 37 (2): 119–37. 1973. doi:10.1111/j.1469-1809.1973.tb01820.x. PMID 4768551.
Hydrolase: esterases (EC 3.1) |
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3.1.1: Carboxylic ester hydrolases |
- Cholinesterase
- Acetylcholinesterase
- Butyrylcholinesterase
- Pectinesterase
- 6-phosphogluconolactonase
- PAF acetylhydrolase
- Lipase
- Bile salt-dependent
- Gastric/Lingual
- Pancreatic
- Lysosomal
- Hormone-sensitive
- Endothelial
- Hepatic
- Lipoprotein
- Monoacylglycerol
- Diacylglycerol
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| 3.1.2: Thioesterase |
- Palmitoyl protein thioesterase
- Ubiquitin carboxy-terminal hydrolase L1
- 4-hydroxybenzoyl-CoA thioesterase
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| 3.1.3: Phosphatase |
- Alkaline phosphatase
- Acid phosphatase (Prostatic)/Tartrate-resistant acid phosphatase/Purple acid phosphatases
- Nucleotidase
- Glucose 6-phosphatase
- Fructose 1,6-bisphosphatase
- Protein phosphatase
- OCRL
- Pyruvate dehydrogenase phosphatase
- fructose 2,6-bisphosphatase
- PTEN
- Phytase
- Inositol-phosphate phosphatase
- Protein phosphatase: Protein tyrosine phosphatase
- Protein serine/threonine phosphatase
- Dual-specificity phosphatase
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3.1.4: Phosphodiesterase |
- Autotaxin
- Phospholipase
- Sphingomyelin phosphodiesterase
- PDE1
- PDE2
- PDE3
- PDE4A/PDE4B
- PDE5
- Lecithinase (Clostridium perfringens alpha toxin)
- Cyclic nucleotide phosphodiesterase
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| 3.1.6: Sulfatase |
- arylsulfatase
- Arylsulfatase A
- Arylsulfatase B
- Arylsulfatase E
- Steroid sulfatase
- Galactosamine-6 sulfatase
- Iduronate-2-sulfatase
- N-acetylglucosamine-6-sulfatase
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Nuclease (includes deoxyribonuclease and ribonuclease) | 3.1.11-16: Exonuclease | | Exodeoxyribonuclease | |
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| Exoribonuclease | |
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3.1.21-31: Endonuclease | | Endodeoxyribonuclease |
- Deoxyribonuclease I
- Deoxyribonuclease II
- Deoxyribonuclease IV
- Restriction enzyme
- UvrABC endonuclease
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| Endoribonuclease |
- RNase III
- RNase H
- RNase P
- RNase A
- RNase T1
- RNA-induced silencing complex
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| either deoxy- or ribo-
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- Nuclease S1
- Serratia marcescens nuclease
- Micrococcal nuclease
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Enzymes |
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| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
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| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
- Enzyme activator
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| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
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| Kinetics |
- Enzyme kinetics
- Eadie–Hofstee diagram
- Hanes–Woolf plot
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
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| Types |
- EC1 Oxidoreductases (list)
- EC2 Transferases (list)
- EC3 Hydrolases (list)
- EC4 Lyases (list)
- EC5 Isomerases (list)
- EC6 Ligases (list)
- EC7 Translocases (list)
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 | Original source: https://en.wikipedia.org/wiki/Methylumbelliferyl-acetate deacetylase. Read more |