Wyandotte, a city of Wayne county, Michigan, U.S.A., on the Detroit river, about 6 m. S. by W. of Detroit. Pop. (1900) 5183, of whom 1267 were foreign-born; (1904) 5425; (1910) 8287. It is served by the Michigan Central, the Lake Shore & Michigan Southern, the Detroit, Toledo && Ironton, and (for freight only) the Detroit & Toledo Shore Line railways, and by two interurban electric lines. Salt and limestone are found here and the city has various manufactures. Wyandotte was first settled about 1820, was laid out as a town in 1854, and chartered as a city in 1867.