Nandrolone Furylpropionate

Nandrolone furylpropionate
Clinical data
Trade names	Demelon
Other names	NFP; Nandrolone 17β-furylpropionate; 19-Nortestosterone 17β-(2-furanyl)propanoate
Routes of; administration	Intramuscular injection
Drug class	Androgen; Anabolic steroid; Androgen ester; Progestogen
Identifiers
	IUPAC name [(8R,9S,10R,13S,14S,17S)-13-methyl-3-oxo-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] 3-(furan-2-yl)propanoate;
CAS Number	7642-64-0;
PubChem CID	111318;
ChemSpider	99880;
UNII	W1309SNY8U;
Chemical and physical data
Formula	C25H32O4
Molar mass	396.527 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2OC(=O)CCC4=CC=CO4)CCC5=CC(=O)CC[C@H]35;
	InChI InChI=1S/C25H32O4/c1-25-13-12-20-19-8-5-17(26)15-16(19)4-7-21(20)22(25)9-10-23(25)29-24(27)11-6-18-3-2-14-28-18/h2-3,14-15,19-23H,4-13H2,1H3/t19-,20+,21+,22-,23-,25-/m0/s1; Key:ICNIVTHKZKRHPD-YNFNDHOQSA-N;

Short description: Chemical compound

Nandrolone furylpropionate (NFP) (JAN) (brand name Demelon), also known as 19-nortestosterone 17β-(2-furanyl)propanoate, is a synthetic androgen and anabolic steroid and a nandrolone ester.^[1]^[2]^[3] It was developed and marketed by Mochida Pharmaceutical in Japan in the 1960s.^[4]^[5]

v · d · e Relative affinities (%) of nandrolone and related steroids
Compound	PR	AR	ER	GR	MR	SHBG	CBG
Nandrolone	20	154–155	<0.1	0.5	1.6	1–16	0.1
Testosterone	1.0–1.2	100	<0.1	0.17	0.9	19–82	3–8
Estradiol	2.6	7.9	100	0.6	0.13	8.7–12	<0.1
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PR, testosterone for the AR, estradiol for the ER, dexamethasone for the GR, aldosterone]] for the MR, dihydrotestosterone for SHBG, and cortisol for CBG. Sources: See template.

References

↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 660–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA660.
↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 716–717. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA716.
↑ Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012. ISBN 978-94-011-4439-1. https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA189.
↑ The Bulletin of Tokyo Medical and Dental University. Tokyo Medical and Dental University. 1965. pp. 342, 344. https://books.google.com/books?id=YA4HAQAAIAAJ.
↑ The Oriental Economist. Oriental Economist. 1969. p. 36. https://books.google.com/books?id=-QlEAQAAIAAJ.

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| group1 = Androgens
(incl. AAS)

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| group2 = Antiandrogens
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  | group1 = AR antagonists
  | list1 =

  | group2 = Steroidogenesis
inhibitors

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  | group3 = Antigonadotropins
  | list3 =

D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (e.g., bifluranol, [[diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, [[cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, [[Chemistry:Medroxyprogesterone medroxyprogesterone acetate, Chemistry:Megestrol acetate|megestrol acetate]])

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Androstenedione immunogens: Androvax (androstenedione albumin)
Ovandrotone albumin (Fecundin)

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^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Androgen receptor modulators; Estrogens and antiestrogens; Progestogens and antiprogestogens; List of androgens/anabolic steroids

}}

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Original source: https://en.wikipedia.org/wiki/Nandrolone furylpropionate. Read more

[Elks2014-1] The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 660–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA660.

[IndexNominum2000-2] Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 716–717. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA716.

[MortonHall2012-3] Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012. ISBN 978-94-011-4439-1. https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA189.

[4] The Bulletin of Tokyo Medical and Dental University. Tokyo Medical and Dental University. 1965. pp. 342, 344. https://books.google.com/books?id=YA4HAQAAIAAJ.

[Ishibashi1969-5] The Oriental Economist. Oriental Economist. 1969. p. 36. https://books.google.com/books?id=-QlEAQAAIAAJ.

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5α-Reductase	Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract
Others	Abiraterone acetate Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel^† Spironolactone

Nandrolone Furylpropionate

See also

References