Methandriol Propionate

Methandriol propionate
Clinical data
Trade names	Metilbisexovis
Other names	Methylandrostenediol propionate; Methylandrostenediol 3β-propionate; 17α-Methylandrost-5-ene-3β,17β-diol 3β-propionate
Routes of; administration	Intramuscular injection
Identifiers
	IUPAC name [(3S,8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13,17-trimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] propanoate;
CAS Number	60883-73-0;
PubChem CID	3085209;
ChemSpider	2342158;
Chemical and physical data
Formula	C23H36O3
Molar mass	360.538 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@]4(C)O)C)C;
	InChI InChI=1S/C23H36O3/c1-5-20(24)26-16-8-11-21(2)15(14-16)6-7-17-18(21)9-12-22(3)19(17)10-13-23(22,4)25/h6,16-19,25H,5,7-14H2,1-4H3/t16-,17+,18-,19-,21-,22-,23-/m0/s1; Key:YAZVIHSCBXWIRW-ZGIWMXSJSA-N;

Short description: Chemical compound

Methandriol propionate (brand name Metilbisexovis), or methylandrostenediol propionate, also known as 17α-methylandrost-5-ene-3β,17β-diol 3β-propionate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a 17α-alkylated derivative of 5-androstenediol that is or was marketed by Vister in Italy.^[1]^[2]^[3] It is an androgen ester – specifically, the C3,17β propionate ester of methandriol (17α-methyl-5-androstenediol) – and acts as a prodrug of methandriol in the body.^[1] Methandriol propionate is administered by intramuscular injection and, relative to methandriol, has an extended duration via this route due to a depot effect afforded by its ester.^{[citation needed]}

References

↑ ^1.0 ^1.1 Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 663–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA663.
↑ Charles D. Kochakian (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. pp. 635–. ISBN 978-3-642-66353-6. https://books.google.com/books?id=3-LrCAAAQBAJ&pg=PA635.
↑ "[Determination and identification of hormonal steroids in pharmaceutical preparations. IV. Solutions of methylandrostenediol propionate and androstenedion dipropionate in oil]". Farmaco Sci 8 (12): 703–5. 1953. PMID 13142030.

{{Navbox

| name = Androgens and antiandrogens
| title = Androgens and antiandrogens
| state = collapsed
| listclass = hlist
| groupstyle = text-align:center;

| group1 = Androgens
(incl. AAS)

| list1 =

| group2 = Antiandrogens
| list2 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 9em;

  | group1 = AR antagonists
  | list1 =

  | group2 = Steroidogenesis
inhibitors

| list2 =

  | group3 = Antigonadotropins
  | list3 =

D₂ receptor antagonists (prolactin releasers) (e.g., domperidone, metoclopramide, risperidone, haloperidol, chlorpromazine, sulpiride)
Estrogens (e.g., bifluranol, [[diethylstilbestrol, estradiol, estradiol esters, ethinylestradiol, ethinylestradiol sulfonate, paroxypropione)
GnRH agonists (e.g., leuprorelin)
GnRH antagonists (e.g., cetrorelix)
Progestogens (incl., chlormadinone acetate, [[cyproterone acetate, hydroxyprogesterone caproate, gestonorone caproate, [[Chemistry:Medroxyprogesterone medroxyprogesterone acetate, Chemistry:Megestrol acetate|megestrol acetate]])

  | group4 = Others
  | list4 =

Androstenedione immunogens: Androvax (androstenedione albumin)
Ovandrotone albumin (Fecundin)

}}

| liststyle = background:#DDDDFF;

| list3 =

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

See also: Androgen receptor modulators; Estrogens and antiestrogens; Progestogens and antiprogestogens; List of androgens/anabolic steroids

}}

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/Methandriol propionate. Read more

[IndexNominum2000-1] 1.0 ^1.1 Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 663–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA663.

[Kochakian2012-2] Charles D. Kochakian (6 December 2012). Anabolic-Androgenic Steroids. Springer Science & Business Media. pp. 635–. ISBN 978-3-642-66353-6. https://books.google.com/books?id=3-LrCAAAQBAJ&pg=PA635.

[pmid13142030-3] "[Determination and identification of hormonal steroids in pharmaceutical preparations. IV. Solutions of methylandrostenediol propionate and androstenedion dipropionate in oil]". Farmaco Sci 8 (12): 703–5. 1953. PMID 13142030.

[1]

[2]

[3]

5α-Reductase	Alfatradiol Dutasteride Epristeride Finasteride Saw palmetto extract
Others	Abiraterone acetate Aminoglutethimide Bifluranol Cyproterone acetate Flutamide Ketoconazole Nilutamide Seviteronel^† Spironolactone

Methandriol Propionate

See also

References