Outer Membrane Efflux Proteins
From Handwiki | Outer membrane efflux protein | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifiers | |||||||||
| Symbol | OEP | ||||||||
| Pfam | PF02321 | ||||||||
| InterPro | IPR003423 | ||||||||
| SCOP2 | 1ek9 / SCOPe / SUPFAM | ||||||||
| TCDB | 1.B.17 | ||||||||
| OPM superfamily | 34 | ||||||||
| OPM protein | 1yc9 | ||||||||
| |||||||||
Proteins in the outer membrane efflux protein family form trimeric (three-piece) channels that allow export of a variety of substrates in gram-negative bacteria. Each member of this family is composed of two repeats. The trimeric channel is composed of a 12-stranded beta-barrel that spans the outer membrane, and a long all helical barrel that spans the periplasm.
Examples include the Escherichia coli TolC outer membrane protein, which is required for proper expression of outer membrane protein genes; the Rhizobium nodulation protein; and the Pseudomonas FusA protein, which is involved in resistance to fusaric acid.
References
- "Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps". Journal of Molecular Biology 287 (3): 695–715. April 1999. doi:10.1006/jmbi.1999.2630. PMID 10092468.
 |  |
Categories: [Protein domains] [Protein families] [Outer membrane proteins]
↧ Download as ZWI file | Last modified: 12/29/2023 21:04:14 | 18 views
☰ Source: https://handwiki.org/wiki/Biology:Outer_membrane_efflux_proteins | License: CC BY-SA 3.0
ZWI signed:
ZWI viewer
by the 
KSF
KSF