| quaternary-ammonium-compound-transporting ATPase |
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| Identifiers |
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| EC number | 3.6.3.32 |
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| Databases |
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| IntEnz | IntEnz view |
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| BRENDA | BRENDA entry |
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| ExPASy | NiceZyme view |
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| KEGG | KEGG entry |
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| MetaCyc | metabolic pathway |
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| PRIAM | profile |
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| PDB structures | RCSB PDB PDBe PDBsum |
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| Gene Ontology | AmiGO / QuickGO |
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| Search |
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| PMC | articles |
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| PubMed | articles |
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| NCBI | proteins |
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In enzymology, a quaternary-amine-transporting ATPase (EC 3.6.3.32) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + quaternary amineout [math]\displaystyle{ \rightleftharpoons }[/math] ADP + phosphate + quaternary aminein
The 3 substrates of this enzyme are ATP, H2O, and quaternary amine, whereas its 3 products are ADP, phosphate, and quaternary amine.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (quaternary-amine-importing). This enzyme participates in abc transporters - general.
References
- "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. 1995. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
- "Lipoprotein from the osmoregulated ABC transport system OpuA of Bacillus subtilis: purification of the glycine betaine binding protein and characterization of a functional lipidless mutant". J. Bacteriol. 179 (20): 6213–20. 1997. PMID 9335265.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol.. Advances in Microbial Physiology 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 978-0-12-027740-7. PMID 9889977.
Hydrolases: acid anhydride hydrolases (EC 3.6) |
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| 3.6.1 |
- Pyrophosphatase
- Apyrase
- Thiamine-triphosphatase
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| 3.6.2 |
- Adenylylsulfatase
- Phosphoadenylylsulfatase
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| 3.6.3-4: ATPase | | 3.6.3 | | Cu++ (3.6.3.4) |
- Menkes/ATP7A
- Wilson/ATP7B
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| Ca+ (3.6.3.8) |
- SERCA
- Plasma membrane
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- SPCA
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| Na+/K+ (3.6.3.9) |
- ATP1A1
- ATP1A2
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP1B4
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| H+/K+ (3.6.3.10) | |
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| Other P-type ATPase |
- ATP8B1
- ATP10A
- ATP11B
- ATP12A
- ATP13A2
- ATP13A3
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| 3.6.4 |
- Dynein
- Kinesin
- Myosin
- Katanin
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| 3.6.5: GTPase | | 3.6.5.1: Heterotrimeric G protein |
- Gαs
- Gαi
- GNAI1
- GNAI2
- GNAI3
- Transducin
- Gustducin
- Gαq/11
- Gα12/13
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| 3.6.5.2: Small GTPase > Ras superfamily |
- Rho family of GTPases: Cdc42
- RhoUV
- Rac
- RhoBTB
- RhoH
- Rho
- Rnd
- RhoDF
- other: Ras
- Rab
- Arf
- Ran
- Rheb
- Rap
- RGK
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| 3.6.5.3: Protein-synthesizing GTPase | |
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| 3.6.5.5-6: Polymerization motors | |
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Enzymes |
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| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
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| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
- Enzyme activator
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| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
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| Kinetics |
- Enzyme kinetics
- Eadie–Hofstee diagram
- Hanes–Woolf plot
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
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| Types |
- EC1 Oxidoreductases (list)
- EC2 Transferases (list)
- EC3 Hydrolases (list)
- EC4 Lyases (list)
- EC5 Isomerases (list)
- EC6 Ligases (list)
- EC7 Translocases (list)
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 | Original source: https://en.wikipedia.org/wiki/Quaternary-amine-transporting ATPase. Read more |