Almagate

Almagate
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	A02AD03 (WHO) ;
Identifiers
CAS Number	66827-12-1;
PubChem CID	71749;
ChemSpider	64792 ;
UNII	568Z59H7ZJ;
KEGG	D02821 ;
Chemical and physical data
Formula	Al2Mg6(OH)14(CO3)2 · 4 H2O
Molar mass	314.99 g/mol
3D model (JSmol)	Interactive image;
	SMILES [Al+3].[Mg+2].[Mg+2].[Mg+2].[OH-].[OH-].[OH-].[O-]C([O-])=O.[OH-].[OH-].[OH-].[OH-].O.O;
	InChI InChI=1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;91H2/q;+3;3+2;;;;;;;;;/p-9 ; Key:MTEOMEWVDVPTNN-UHFFFAOYSA-E ;
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Short description: Chemical compound

Almagate (trade name Almax) is an aluminium- and magnesium-containing antacid. It was first described in 1984.^[1]^[2]

Adverse effects

Almagate is well tolerated. In a clinical trial, the most common adverse effects were diarrhea and nausea.^[3]

↑ "Characterization of a new crystalline synthetic gastric antacid, almagate" (Free full text). Arzneimittel-Forschung 34 (10A): 1346–9. 1984. PMID 6548918. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.
↑ "Evaluation of a new antacid, almagate" (Free full text). Arzneimittel-Forschung 34 (10A): 1350–4. 1984. PMID 6439224. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.
↑ "Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A multicentre clinical trial" (Free full text). Arzneimittel-Forschung 34 (10A): 1380–3. 1984. PMID 6548926. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2.

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Original source: https://en.wikipedia.org/wiki/Almagate. Read more

v t e Drugs for acid related disorders: Antacids (A02A)
Magnesium (increases motility)	Magnesium carbonate Magnesium oxide Magnesium peroxide Magnesium hydroxide Magnesium silicate
Aluminium (decreases motility)	Aceglutamide aluminum Algeldrate Aluminium phosphate Aluminium acetoacetate Aloglutamol Aluminium glycinate Carbaldrate
Calcium	Calcium carbonate Calcium silicate
Sodium	Sodium bicarbonate
Combinations and complexes of aluminium, calcium and magnesium	Almagate Almasilate Hydrotalcite Magaldrate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	A02AD03 (WHO)
Identifiers
CAS Number	66827-12-1
PubChem CID	71749
ChemSpider	64792^Y
UNII	568Z59H7ZJ
KEGG	D02821^Y
Chemical and physical data
Formula	Al₂Mg₆(OH)₁₄(CO₃)₂ · 4 H₂O
Molar mass	314.99 g/mol
3D model (JSmol)	Interactive image
SMILES [Al+3].[Mg+2].[Mg+2].[Mg+2].[OH-].[OH-].[OH-].[O-]C([O-])=O.[OH-].[OH-].[OH-].[OH-].O.O
InChI InChI=1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;91H2/q;+3;3+2;;;;;;;;;/p-9^Y Key:MTEOMEWVDVPTNN-UHFFFAOYSA-E^Y
(verify)