| glucosamine kinase |
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| Identifiers |
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| EC number | 2.7.1.8 |
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| CAS number | 9031-90-7 |
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| Databases |
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| IntEnz | IntEnz view |
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| BRENDA | BRENDA entry |
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| ExPASy | NiceZyme view |
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| KEGG | KEGG entry |
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| MetaCyc | metabolic pathway |
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| PRIAM | profile |
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| PDB structures | RCSB PDB PDBe PDBsum |
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| Gene Ontology | AmiGO / QuickGO |
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| Search |
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| PMC | articles |
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| PubMed | articles |
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| NCBI | proteins |
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In enzymology, a glucosamine kinase (EC 2.7.1.8) is an enzyme that catalyzes the chemical reaction
- ATP + D-glucosamine [math]\displaystyle{ \rightleftharpoons }[/math] ADP + D-glucosamine phosphate
Thus, the two substrates of this enzyme are ATP and D-glucosamine, whereas its two products are ADP and D-glucosamine phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-glucosamine phosphotransferase. Other names in common use include glucosamine kinase (phosphorylating), ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase, and aminodeoxyglucose kinase. This enzyme participates in aminosugars metabolism.
References
- "Hexokinases of Schistosoma mansoni". J. Biol. Chem. 215 (2): 495–506. 1955. PMID 13242546.
Transferases: phosphorus-containing groups (EC 2.7) |
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2.7.1-2.7.4:
phosphotransferase/kinase
(PO4) | | 2.7.1: OH acceptor |
- Hexo-
- Gluco-
- Fructo-
- Galacto-
- Phosphofructo-
- 1
- Liver
- Muscle
- Platelet
- 2
- Riboflavin
- Shikimate
- Thymidine
- NAD+
- Glycerol
- Pantothenate
- Mevalonate
- Pyruvate
- Deoxycytidine
- PFP
- Diacylglycerol
- Phosphoinositide 3
- Class I PI 3
- Class II PI 3
- Sphingosine
- Glucose-1,6-bisphosphate synthase
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| 2.7.2: COOH acceptor |
- Phosphoglycerate
- Aspartate kinase
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| 2.7.3: N acceptor | |
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| 2.7.4: PO4 acceptor |
- Phosphomevalonate
- Adenylate
- Nucleoside-diphosphate
- Uridylate
- Guanylate
- Thiamine-diphosphate
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2.7.6: diphosphotransferase
(P2O7) |
- Ribose-phosphate diphosphokinase
- Thiamine diphosphokinase
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2.7.7: nucleotidyltransferase
(PO4-nucleoside) | | Polymerase | | DNA polymerase |
- DNA-directed DNA polymerase
- I/A
- γ
- θ
- ν
- T7
- Taq
- II/B
- α
- δ
- ε
- ζ
- Pfu
- III/C
- IV/X
- β
- λ
- μ
- TDT
- V/Y
- η
- ι
- κ
- RNA-directed DNA polymerase
- Reverse transcriptase
- Telomerase
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| RNA nucleotidyltransferase |
- Template-directed
- RNA polymerase I
- II
- III
- IV
- V
- ssRNAP
- POLRMT
- Primase
- 1
- 2
- PrimPol
- RNA-dependent RNA polymerase
- Polyadenylation
- PAP
- PNPase
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Phosphorolytic
3' to 5' exoribonuclease | |
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| Nucleotidyltransferase |
- UTP—glucose-1-phosphate uridylyltransferase
- Galactose-1-phosphate uridylyltransferase
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| Guanylyltransferase | |
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| Other |
- Recombinase (Integrase)
- Transposase
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| 2.7.8: miscellaneous | | Phosphatidyltransferases |
- CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase
- CDP-diacylglycerol—serine O-phosphatidyltransferase
- CDP-diacylglycerol—inositol 3-phosphatidyltransferase
- CDP-diacylglycerol—choline O-phosphatidyltransferase
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| Glycosyl-1-phosphotransferase |
- N-acetylglucosamine-1-phosphate transferase
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2.7.10-2.7.13: protein kinase
(PO4; protein acceptor) | | 2.7.10: protein-tyrosine | |
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| 2.7.11: protein-serine/threonine |
- see serine/threonine-specific protein kinases
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| 2.7.12: protein-dual-specificity |
- see serine/threonine-specific protein kinases
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| 2.7.13: protein-histidine |
- Protein-histidine pros-kinase
- Protein-histidine tele-kinase
- Histidine kinase
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Enzymes |
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| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
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| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
- Enzyme activator
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| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
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| Kinetics |
- Enzyme kinetics
- Eadie–Hofstee diagram
- Hanes–Woolf plot
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
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| Types |
- EC1 Oxidoreductases (list)
- EC2 Transferases (list)
- EC3 Hydrolases (list)
- EC4 Lyases (list)
- EC5 Isomerases (list)
- EC6 Ligases (list)
- EC7 Translocases (list)
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 | Original source: https://en.wikipedia.org/wiki/Glucosamine kinase. Read more |
From Handwiki 
KSF