Lewisburg, a borough and the county-seat of Union county, Pennsylvania, U.S.A., on the W. bank of West Branch of the Susquehanna river, about 50 m. N. of Harrisburg. Pop. (1900) 3457 (60 foreign-born); (1910) 3081. It is served by the Pennsylvania and the Philadelphia & Reading railways. It is the seat of Bucknell University (coeducational), opened in 1846 as the university of Lewisburg and renamed in 1886 in honour of William Bucknell (1809-1890), a liberal benefactor. The university comprises a College of Liberal Arts, an Academy for Young Men, an Institute for Young Women, and a School of Music, and in 1908-1909 had 50 instructors and 775 students, of whom 547 were in the College of Liberal Arts. The city is situated in a farming region, and has various manufactures, including flour, lumber, furniture, woollens, nails, foundry products and carriages. Lewisburg (until about 1805 called Derrstown) was founded and laid out in 1785 by Ludwig Derr, a German, and was chartered as a borough in 1812.