List Of Adverse Effects Of Sertraline

Adverse effects of sertraline by incidence.^[1]^[2]^[3]^[4]

Very common (>10%)[edit | edit source]

Common (1-10%)[edit | edit source]

Agitation
Anorexia
Constipation
Dyspepsia (indigestion)
Decreased libido
Sweating
Tremor
Vomiting
Impaired concentration
Nervousness
Paroniria (i.e., depraved or morbid dreaming/nightmares)
Yawning
Palpitations
Increased sweating
Hot flushes
Weight decrease
Weight increase
Myoclonus
Hypertonia
Bruxism (teeth grinding)
Hypoaesthesia
Menstrual irregularities
Sexual dysfunction
Rash
Vision abnormal
Asthenia
Chest pain
Paraesthesia
Tinnitus (hearing ringing in the ears)
Birth defects (if taken during pregnancy), this includes:
- Heart defects,
- Cleft lip,
- Cleft palate,
- Clubbed feet,
- Omphalocele hydrocephalus and any other birth defects.

Uncommon (0.1-1%)[edit | edit source]

Hypertension (high blood pressure)
Hyperkinesia
Bronchospasm
Oesophagitis (swollen oesophagus)
Dysphagia
Haemorrhoids
Purpura
Cold Sweat
Dry skin
Nocturia
Urinary Retention
Polyuria (excessive urination)
Vaginal Haemorrhage
Malaise
Chills
Pyrexia (fever)
Thirst
Pollakiuria
Micturition disorder
Salivary Hypersecretion
Tongue Disorder
Osteoarthritis
Muscular Weakness
Back Pain
Muscle Twitching
Eructation (belching)
Dyspnoea (air hunger)
Epistaxis (nose bleed)
Edema peripheral
Periorbital Edema
Syncope
Postural dizziness
Tachycardia (high heart rate)
Urticaria (hives)
Migraine
Abnormal bleeding (esp. in the GI tract)
Muscle cramps
Arthralgia
Depressive symptoms
Euphoria
Hallucination
Alopecia (hair loss)
Urinary Retention (being unable to pass urine)
Pruritus
Amnesia memory loss.
Urinary incontinence
Eye pain
Asymptomatic elevations in serum transaminases
Abnormal semen
Melaena (black faeces due to a bleed in the stomach)
Coffee ground vomiting
Haematochezia
Stomatitis (swollen mouth)
Tongue ulceration
Tooth Disorder
Glossitis (soreness/swelling of the tongue)
Mouth Ulceration
Laryngospasm
Hyperventilation (breathing more often than required to keep one's blood sufficiently oxygenated)
Hypoventilation (breathing less often than required to keep one's blood sufficiently oxygenated)
Stridor
Dysphonia (voice disorder)
Upper Respiratory Tract Infection
Rhinitis (irritation/inflammation inside the nose)
Hiccups
Apathy
Thinking Abnormal

Rare (<0.1%)[edit | edit source]

Allergic reaction
Allergy
Anaphylactoid reaction
Face oedema
Priapism
facial hyperpigmentation
Atrial arrhythmia
AV block
Coma
Peripheral Ischaemia
Injury
Vasodilation Procedure
Lymphadenopathy
Involuntary muscle contractions
Galactorrhoea (lactation that is unrelated to pregnancy or breastfeeding)
Gynaecomastia (swelling of breast tissue in men)
Hyperprolactinaemia (high blood prolactin levels)
Hypothyroidism (underactive thyroid gland)
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
Pancreatitis (swollen pancreas)
Altered platelet function
Haematuria (blood in the urine)
Leukopenia (low white blood cell count)
Thrombocytopenia (low blood platelet count)
Increased coagulation times
Abnormal clinical laboratory results
Hyponatraemia (low blood sodium)
Conversion Disorder
Drug Dependence
Paranoia
Myocardial Infarction (heart attack)
Bradycardia
Cardiac Disorder
Suicidal Ideation/behaviour
Sleep Walking
Premature Ejaculation
Hyperglycemia (high blood sugar)
Hypoglycemia (low blood sugar)
Hypercholesterolaemia (high blood cholesterol)
Vasculitis
Aggressive reaction
Psychosis (hallucinations and delusions)
Mania (a dangerously elated mood)
Menorrhagia (an abnormally excessive amount of menstrual bleeding)
Atrophic Vulvovaginitis
Balanoposthitis
Genital Discharge
Angioedema
Photosensitivity skin reaction
Enuresis
Visual field defect
Abnormal liver function
Dermatitis
Dermatitis Bullous
Rash Follicular
Glaucoma
Lacrimal Disorder
Scotoma
Diplopia
Photophobia
Hyphaema
Mydriasis
Hair Texture Abnormal
Neoplasm
Diverticulitis
Choreoathetosis
Dyskinesia
Hyperaesthesia
Sensory Disturbance
Gastroenteritis
Otitis Media
Skin Odour Abnormal

Unknown frequency[edit | edit source]

QTc prolongation
Allergic Reaction
Allergy
Neuroleptic malignant syndrome. A potentially fatal reaction that most often occurs as a result of the use of antipsychotic drugs. It is characterised by fever, muscle rigidity, rhabdomyolysis (muscle breakdown), profuse sweating, tachycardia, tachypnoea (rapid breathing), agitation.
Stevens–Johnson syndrome a potentially fatal skin reaction.
Toxic epidermal necrolysis another potentially fatal skin reaction.
Torsades de pointes a potentially fatal change in the heart's rhythm.
Cerebrovascular spasm
Serotonin syndrome similar to neuroleptic malignant syndrome but develops more rapidly (over a period of hours instead of days/weeks for neuroleptic malignant syndrome)
Bone fracture
Movement disorders
Diabetes mellitus
Dyspnoea
Jaundice yellowing of the skin, mucous membranes and eyes due to an impaired ability of the liver to clear the haem breakdown by product, bilirubin.
Hepatitis
Liver failure
Persistent Sexual Dysfunction

References[edit | edit source]

↑ "Zoloft (sertraline) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 2 October 2013. Retrieved 30 September 2013.
↑ "PRODUCT INFORMATION ZOLOFT (sertraline hydrochloride)" (PDF). TGA eBusiness Services. Pfizer Australia Pty Ltd. 28 May 2013. Archived from the original on 7 August 2013. Retrieved 30 September 2013.
↑ "Sertraline 100mg Film coated Tablets - Summary of Product Characteristics (SPC)". electronic Medicines Compendium. Accord Healthcare Limited. 25 August 2013. Archived from the original on 2 December 2013. Retrieved 27 November 2013.
↑ "ZOLOFT (sertraline hydrochloride) tablet, film coated [PD-Rx Pharmaceuticals, Inc.]". DailyMed. PD-Rx Pharmaceuticals, Inc. September 2011. Archived from the original on 2 December 2013. Retrieved 27 November 2013.

[MSR-1] "Zoloft (sertraline) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 2 October 2013. Retrieved 30 September 2013.

[TGA-2] "PRODUCT INFORMATION ZOLOFT (sertraline hydrochloride)" (PDF). TGA eBusiness Services. Pfizer Australia Pty Ltd. 28 May 2013. Archived from the original on 7 August 2013. Retrieved 30 September 2013.

[EMC-3] "Sertraline 100mg Film coated Tablets - Summary of Product Characteristics (SPC)". electronic Medicines Compendium. Accord Healthcare Limited. 25 August 2013. Archived from the original on 2 December 2013. Retrieved 27 November 2013.

[DM-4] "ZOLOFT (sertraline hydrochloride) tablet, film coated [PD-Rx Pharmaceuticals, Inc.]". DailyMed. PD-Rx Pharmaceuticals, Inc. September 2011. Archived from the original on 2 December 2013. Retrieved 27 November 2013.

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