Topical Decongestant

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Short description: Decongestants applied in nose

Topical decongestants are decongestants applied directly to the nasal cavity. Their effectiveness by themselves in the common cold appears to have a small benefit in adults.[1]

Topical decongestants should only be used by patients for a maximum of 5–7 days in a row, because rebound congestion may occur in the form of rhinitis medicamentosa. When used in adults for a short period of time side effects appear to be few.[1]

Mechanism of action

Topical decongestants are vasoconstrictors, and work by constricting the blood vessels within the nasal cavity.

Examples

  • Ephedrine
  • Levomethamphetamine
  • Naphazoline
  • Oxymetazoline
  • Phenylephrine
  • Pseudoephedrine
  • Tramazoline
  • Xylometazoline

See also

  • Decongestant
  • Nasal irrigation
  • Nasal spray

References

  1. 1.0 1.1 Deckx, L; De Sutter, AI; Guo, L; Mir, NA; van Driel, ML (17 October 2016). "Nasal decongestants in monotherapy for the common cold.". The Cochrane Database of Systematic Reviews 10: CD009612. doi:10.1002/14651858.CD009612.pub2. PMID 27748955. 




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Categories: [Topical decongestants]


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