Further information: Chemistry:Norepinephrine releasing agent and Chemistry:Dopamine releasing agent
A norepinephrine–dopamine releasing agent (NDRA) is a type of drug which induces the release of norepinephrine (and epinephrine) and dopamine in the body and/or brain.
Examples of NDRAs include phenethylamine, tyramine, amphetamine, methamphetamine, lisdexamfetamine, cathinone, methcathinone, propylhexedrine, phenmetrazine, pemoline, 4-methylaminorex, and benzylpiperazine.
A closely related type of drug is a norepinephrine–dopamine reuptake inhibitor (NDRI).
See also
- Monoamine releasing agent
References
External links
Monoamine releasing agents |
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| DRAs | |
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| NRAs | |
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| SRAs | |
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| Others |
- Monoamine activity enhancers: BPAP
- PPAP
- DAT modulators: Agonist-like: SoRI-9804
- SoRI-20040; Antagonist-like: SoRI-20041
- Adrenergic release blockers: Bethanidine
- Bretylium
- Guanadrel
- Guanazodine
- Guanethidine
- Guanoxan
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See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |
Human trace amine-associated receptor ligands |
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| TAAR1 | | Agonists | | Endogenous† |
- Classical monoamine neurotransmitters
- Dopamine
- Histamine
- Norepinephrine
- Serotonin
- Trace amines
- 3-Iodothyronamine
- 3-Methoxytyramine
- N-Methylphenethylamine
- N-Methyltyramine
- m-Octopamine
- p-Octopamine
- Phenethylamine
- Phenylethanolamine
- Synephrine
- Tryptamine
- m-Tyramine
- p-Tyramine
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| Synthetic‡ |
- Amphetamine
- DOB
- DOET
- 4-Hydroxyamphetamine
- Isoprenaline
- MDA (tenamfetamine)
- MDMA (midomafetamine)
- 2-Methylphenethylamine
- 3-Methylphenethylamine
- 4-Methylphenethylamine
- β-Methylphenethylamine
- Methamphetamine
- 3-MMA
- Norfenfluramine
- Phentermine
- o-PIT
- Propylhexedrine
- RO5166017
- N,N-Dimethylphenethylamine
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| Neutral antagonists | |
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| Inverse agonists | |
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| TAAR2 | | Agonists‡ | |
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| Neutral antagonists | |
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| TAAR5 | | Agonists‡ |
- N,N-Dimethylethylamine
- Trimethylamine
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| Neutral antagonists | |
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| Inverse agonists‡ | |
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† References for all endogenous human TAAR1 ligands are provided at List of trace amines
‡ References for synthetic TAAR1 agonists can be found at TAAR1 or in the associated compound articles. For TAAR2 and TAAR5 agonists and inverse agonists, see TAAR for references.
See also: Receptor/signaling modulators |
 | Original source: https://en.wikipedia.org/wiki/Norepinephrine–dopamine releasing agent. Read more |
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