Octyl Salicylate

Octyl salicylate

Names
IUPAC name 2-ethylhexyl 2-hydroxybenzoate
Other names octisalate; 2-ethylhexyl salicylate; ethyl hexyl salicylate; 2-ethylhexyl ester salicylic acid; salicylic acid, 2-ethylhexyl ester; benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; 2-ethylhexyl ester benzoic acid, 2-hydroxy-; 2-hydroxy- 2-ethylhexyl ester benzoic acid;
Identifiers
CAS Number	118-60-5 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL117388 Y
ChemSpider	8061 N
PubChem CID	8364
UNII	4X49Y0596W Y
InChI InChI=1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3 N Key: FMRHJJZUHUTGKE-UHFFFAOYSA-N N InChI=1/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3 Key: FMRHJJZUHUTGKE-UHFFFAOYAL
SMILES CCCCC(CC)COC(=O)C1=CC=CC=C1O
Properties
Chemical formula	C15H22O3
Molar mass	250.33 g/mol
Density	1.014 g/cm3
Melting point	< 25 °C (77 °F; 298 K)
Boiling point	189 °C (372 °F; 462 K)
Hazards
NFPA 704 (fire diamond)	1 1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Octyl salicylate, or 2-ethylhexyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun.^[1] It is an ester formed by the condensation of salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor.

The salicylate portion of the molecule absorbs ultraviolet light, protecting skin from the harmful effects of exposure to sunlight. The ethylhexanol portion is a fatty alcohol, adding emollient and oil-like (water resistant) properties.

Octisalate and all other salicylates have a good safety profile.^[2] It is often used to improve affinity and reduce photodegradation of other sunscreen ingredients (such as oxybenzone and avobenzone), and <1% of the applied dose of Octisalate penetrates through the skin. Although Octisalate is a weaker UVB absorber it has superior stability than some other sunscreen active ingredients^[3] and does not produce reactive oxygen species when exposed to sunlight. However, it does have some minor sensitization potential; with some individuals experiencing minimal to mild skin irritation.^[4]

• "The Skin Cancer Foundation's Guide to Sunscreens". Skin Cancer Foundation. 2011. http://www.skincancer.org/the-scfs-guide-to-sunscreens.html. 

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