Tetracyclic

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Short description: Organic compound having 4 fused rings
Doxycycline, a tetracyclic antibiotic.
Mirtazapine, a tetracyclic antidepressant.

Tetracyclics are cyclic chemical compounds that contain four fused rings of atoms, for example, Tröger's base.

Some tricyclic compounds having three fused and one tethered ring (connected to main nucleus by a single bond) can also classified as tetracyclic, for example, ciclazindol.[1]

They have various pharmaceutical uses, such as:

  • tetracycline antibiotics
    • Doxycycline
    • Tigecycline
    • Omadacycline
    • Eravacycline
  • tetracyclic antidepressants
    • Benzoctamine
    • Loxapine
    • Mazindol
    • Mianserin
    • Mirtazapine[2]

See also

  • Tricyclic
  • Heterocyclic

References

  1. Wheatley, David (1982-05-01). "A new weight-reducing drug with novel properties" (in en). Postgraduate Medical Journal 58 (679): 279–281. doi:10.1136/pgmj.58.679.279. ISSN 0032-5473. PMID 7050949. PMC 2426414. https://pmj.bmj.com/content/58/679/279. 
  2. Jilani, Talha N.; Gibbons, Jonathan R.; Faizy, Rubina M.; Saadabadi, Abdolreza (2022). Mirtazapine. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK519059/#:~:text=Mirtazapine is an atypical antidepressant,release of serotonin and norepinephrine.. Retrieved 2023-01-03. 



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Categories: [Tetracyclic compounds]


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