Lengsin
From Handwiki  Generic protein structure example |
Lengsin is a protein that in humans is encoded by the LGSN gene.
Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re-engineering for a tissue-specific, noncatalytic role in the lens of the vertebrate eye.[1] Lengsin is the result of the recruitment of an ancient enzyme may act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. It does not seem to have enzymatic activity.
References
- ↑ "A role for lengsin, a recruited enzyme, in terminal differentiation in the vertebrate lens". The Journal of Biological Chemistry 283 (10): 6607–15. March 2008. doi:10.1074/jbc.M709144200. PMID 18178558.
Further reading
- "Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens". Structure (London, England) 14 (12): 1823–34. December 2006. doi:10.1016/j.str.2006.10.008. PMID 17161372.
External links
- "Q5TDP6 (LGSN_HUMAN)". UniProtKB. https://www.uniprot.org/uniprot/Q5TDP6.
 |
Categories: [Proteins]
↧ Download as ZWI file | Last modified: 08/11/2024 22:44:37 | 25 views
☰ Source: https://handwiki.org/wiki/Biology:Lengsin | License: CC BY-SA 3.0
✘
ZWI is not signed. [what is this?]
ZWI viewer
by the 
KSF
KSF