To prohibit something is to make a proclamation, edict or law that a certain activity should not be undertaken. This may range from a simple statement by parents that their children should not see a particular friend because of undesirable characteristics to commandments from God which for example prohibit children marrying their parents or working on the sabbath.
During the 1920s the American government imposed a ban on the manufacture and sale of alcohol. This was known as Prohibition.
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