4-(4-Methylphenyl)-4-Oxobutanoic Acid

4-(4-Methylphenyl)-4-oxobutanoic acid
Names
	Preferred IUPAC name 4-(4-Methylphenyl)-4-oxobutanoic acid
	Other names 3-(4-Methylbenzoyl)propionic acid; 3-(p-Toluoyl)propionic acid; 4-(4-Methylphenyl)-4-oxobutyric acid
Identifiers
CAS Number	4619-20-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	213498 ;
EC Number	610-285-9;
PubChem CID	244162;
UNII	ZYB7JU7CMX;
	InChI InChI=1S/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14) Key: OEEUWZITKKSXAZ-UHFFFAOYSA-N ; InChI=1/C11H12O3/c1-8-2-4-9(5-3-8)10(12)6-7-11(13)14/h2-5H,6-7H2,1H3,(H,13,14) Key: OEEUWZITKKSXAZ-UHFFFAOYAH;
	SMILES O=C(c1ccc(cc1)C)CCC(=O)O;
Properties
Chemical formula	C11H12O3
Molar mass	192.214 g·mol−1
Appearance	White powder
Melting point	129 °C (264 °F; 402 K)
Solubility in water	Insoluble
Hazards
Main hazards	Flammable
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H315, H319, H335
GHS precautionary statements	P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P332+313, P337+313, P362, P403+233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid. The preparation of it is used for undergraduate teaching of organic chemistry synthesis.

Preparation

4-(4-Methylphenyl)-4-oxobutanoic acid can be prepared by a Friedel–Crafts reaction between toluene and succinic anhydride catalyzed by a Lewis acid such as aluminium chloride.^[2]

References

↑ "3-(4-Methylbenzoyl)propionic acid" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/244162#section=Safety-and-Hazards.
↑ Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.

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Original source: https://en.wikipedia.org/wiki/4-(4-Methylphenyl)-4-oxobutanoic acid. Read more

[1] "3-(4-Methylbenzoyl)propionic acid" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/244162#section=Safety-and-Hazards.

[2] Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.

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