In physics, a paste is a substance that behaves as a solid until a sufficiently large load or stress is applied, at which point it flows like a fluid. In rheological terms, a paste is an example of a Bingham plastic fluid.
Pastes typically consist of a suspension of granular material in a background fluid. The individual grains are jammed together like sand on a beach, forming a disordered, glassy or amorphous structure, and giving pastes their solid-like character. It is this "jamming together" that gives pastes some of their most unusual properties; this causes paste to demonstrate properties of fragile matter.
Examples include starch pastes, toothpaste, mustard, and putty.
In pharmacology, paste is a basic pharmaceutical form. It consists of a fatty base (e.g., petroleum jelly) and at least 25% of a solid substance (e.g., zinc oxide). Pharmaceutical pastes are typically intended for external application to the skin. They are usually thick and do not melt at physiologic temperatures.[1]
References
- ↑ Juch, R & Rufli, Th & Surber, Christian. (1994). Pastes: What Do They Contain? How Do They Work?. Dermatology (Basel, Switzerland). 189. 373-7. doi:10.1159/000246882.
Routes of administration, dosage forms |
|---|
| Oral | Digestive tract (enteral) | | Solids |
- Pill
- Tablet
- Capsule
- Pastille
- Time release technology
- Osmotic delivery system (OROS)
| |
|---|
| Liquids |
- Decoction
- Elixir
- Electuary
- Emulsion
- Extended-release syrup
- Effervescent powder or tablet
- Herbal tea
- Hydrogel
- Molecular encapsulation
- Powder
- Softgel
- Solution
- Suspension
- Syrup
- Syrup Concentrate for dilution and/or addition of carbonated water
- Tincture
|
|---|
|
|---|
Buccal (sublabial), sublingual | | Solids |
- Orally disintegrating tablet (ODT)
- Film
- Lollipop
- Sublingual drops
- Lozenges
- Effervescent buccal tablet
- Chewing gum
|
|---|
| Liquids |
- Mouthwash
- Toothpaste
- Ointment
- Oral spray
|
|---|
|
|---|
Respiratory tract | | Solids |
- Smoking device
- Dry-powder inhaler (DPI)
| 00 |
|---|
| Liquids |
- Anaesthetic vaporizer
- Vaporizer
- Nebulizer
- Metered-dose inhaler (MDI)
|
|---|
| Gas |
- Oxygen mask and Nasal cannula
- Oxygen concentrator
- Anaesthetic machine
- Relative analgesia machine
|
|---|
|
|---|
|
|---|
Ophthalmic, otologic, nasal]] |
- Nasal spray
- Ear drops
- Eye drops
- Ointment
- Hydrogel
- Nanosphere suspension
- Insufflation
- Mucoadhesive microdisc (microsphere tablet)
|
|---|
| Urogenital |
Ointment
Pessary (vaginal suppository)
Vaginal ring
Vaginal douche
Intrauterine device (IUD)
Extra-amniotic infusion
Intravesical infusion
|
|---|
| Rectal (enteral) |
- Ointment
- Suppository
- Enema
- Murphy drip
- Nutrient enema
|
|---|
| Dermal |
Ointment
Topical cream
Topical gel
Liniment
Paste
Film
DMSO drug solution
Electrophoretic dermal delivery system
Hydrogel
Liposomes
Transfersome vesicles
Cream
Lotion
Lip balm
Medicated shampoo
Dermal patch
Transdermal patch
Contact (rubbed into break in the skin)
Transdermal spray
Jet injector |
|---|
Injection, infusion<br />(into tissue/blood) | | Skin |
Intradermal
Subcutaneous
Transdermal implant
| |
|---|
| Organs |
- Intracavernous
- Intravitreal
- Intra-articular injection
- Transscleral
|
|---|
| Central nervous system |
- Intracerebral
- Intrathecal
- Epidural
|
|---|
Circulatory, musculoskeletal |
- Intravenous
- Intracardiac
- Intramuscular
- Intraosseous
- Intraperitoneal
- Nanocell injection
- Patient-controlled analgesia pump
- PIC line
|
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|
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 | Original source: https://en.wikipedia.org/wiki/Paste (rheology). Read more |