Antipsychotic Ester

From Handwiki

Short description: Class of prodrugs
Haloperidol decanoate, an antipsychotic ester.

An antipsychotic ester is an ester of an antipsychotic.[1] They are used clinically as prodrugs to increase fat solubility and thereby prolong duration when antipsychotics are used as depot injectables.[1]

List of clinically used antipsychotic esters

Typical antipsychotics

  • Bromperidol decanoate
  • Clopentixol decanoate
  • Flupentixol decanoate
  • Fluphenazine decanoate
  • Fluphenazine enanthate
  • Haloperidol decanoate
  • Oxyprothepin decanoate
  • Perphenazine decanoate
  • Perphenazine enanthate
  • Pipotiazine palmitate
  • Pipotiazine undecylenate
  • Zuclopentixol acetate
  • Zuclopentixol decanoate

Atypical antipsychotics

  • Aripiprazole lauroxil
  • Paliperidone palmitate

Pharmacology

References

  1. 1.0 1.1 "The pharmacokinetics of long-acting antipsychotic medications". Current Clinical Pharmacology 9 (3): 310–7. 2014. doi:10.2174/15748847113089990051. PMID 23343447. 




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Categories: [Antipsychotic esters]


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