Environment-Wide Association Study

Short description: Type of epidemiological study

An environment-wide association study, also known as an environmental-wide association study (abbreviated EWAS), is a type of epidemiological study analogous to the genome-wide association study, or GWAS. The EWAS systematically examines the association between a complex disease and multiple individual environmental factors, controlling for multiple hypothesis testing.^[1]^[2]^[3]

References

↑ Patel, Chirag J.; Bhattacharya, Jayanta; Butte, Atul J. (2010-05-20). Zhang, Baohong. ed. "An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus" (in en). PLOS ONE 5 (5): e10746. doi:10.1371/journal.pone.0010746. ISSN 1932-6203. PMID 20505766. Bibcode: 2010PLoSO...510746P.
↑ Zhuang, Xiaodong; Ni, Ao; Liao, Lizhen; Guo, Yue; Dai, Wei; Jiang, Yunxi; Zhou, Huimin; Hu, Xun et al. (February 2018). "Environment-wide association study to identify novel factors associated with peripheral arterial disease: Evidence from the National Health and Nutrition Examination Survey (1999–2004)" (in en). Atherosclerosis 269: 172–177. doi:10.1016/j.atherosclerosis.2018.01.006. PMID 29366990.
↑ McGinnis, Denise P.; Brownstein, John S.; Patel, Chirag J. (September 2016). "Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999–2012)" (in en). Scientific Reports 6 (1): 30373. doi:10.1038/srep30373. ISSN 2045-2322. PMID 27457472. Bibcode: 2016NatSR...630373M.

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[1] Patel, Chirag J.; Bhattacharya, Jayanta; Butte, Atul J. (2010-05-20). Zhang, Baohong. ed. "An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus" (in en). PLOS ONE 5 (5): e10746. doi:10.1371/journal.pone.0010746. ISSN 1932-6203. PMID 20505766. Bibcode: 2010PLoSO...510746P.

[2] Zhuang, Xiaodong; Ni, Ao; Liao, Lizhen; Guo, Yue; Dai, Wei; Jiang, Yunxi; Zhou, Huimin; Hu, Xun et al. (February 2018). "Environment-wide association study to identify novel factors associated with peripheral arterial disease: Evidence from the National Health and Nutrition Examination Survey (1999–2004)" (in en). Atherosclerosis 269: 172–177. doi:10.1016/j.atherosclerosis.2018.01.006. PMID 29366990.

[3] McGinnis, Denise P.; Brownstein, John S.; Patel, Chirag J. (September 2016). "Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999–2012)" (in en). Scientific Reports 6 (1): 30373. doi:10.1038/srep30373. ISSN 2045-2322. PMID 27457472. Bibcode: 2016NatSR...630373M.