Tug1

From Handwiki

Short description: Non-coding RNA in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example


TUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in a screen for genes upregulated by in developing retinal cells in response to taurine. It is required for the normal development of photoreceptors in the retina.[1]

See also

  • Long noncoding RNA

References

  1. "The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina". Curr. Biol. 15 (6): 501–512. March 2005. doi:10.1016/j.cub.2005.02.027. PMID 15797018. 

Further reading

  • "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. 1996. doi:10.1101/gr.6.9.791. PMID 8889548. 
  • "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.". Biochem. Biophys. Res. Commun. 345 (3): 1022–1032. 2006. doi:10.1016/j.bbrc.2006.04.175. PMID 16712791. 
  • "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
  • "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–716. 2004. doi:10.1038/nbt971. PMID 15146197. 
  • "Identification of genes differentially expressed in B16 murine melanoma sublines with different metastatic potentials.". Cancer Res. 56 (4): 875–879. 1996. PMID 8631027. 
  • "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–45. 2004. doi:10.1038/ng1285. PMID 14702039. 



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Categories: [Non-coding RNA]


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