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1. Inheritors (play): Inheritors is a four-act play written by the American dramatist Susan Glaspell, first performed in 1921 (103 years ago) (1921). The play concerns the legacy of an idealistic farmer who wills his highly coveted midwest farmland to the establishment ... (Play) [100%] 2024-01-01 [1921 plays] [Plays by Susan Glaspell]...
2. PCSK9 inhibitors: PCSK9 inhibitors are a class of medications used to treat hypercholesterolemia. In those on high doses of statins, they decrease risk of further problems by 1.5% over 2.5 years. [88%] 2024-01-01
3. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... (Chemistry) [88%] 2023-12-17 [Protein kinase inhibitors]
4. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... [88%] 2024-02-11 [Protein kinase inhibitors]
5. Lipase inhibitors: Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. [88%] 2023-12-19 [Lipase inhibitors] [Obesity]...
6. Protease inhibitors: Protease inhibitors (PIs) are a class of medication used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 protease, an enzyme used by the viruses to ... [88%] 2023-10-09 [Antivirals] [Antiretroviral drugs]...
7. Phosphodiesterase inhibitors: Articles Most recent articles on Phosphodiesterase inhibitors Most cited articles on Phosphodiesterase inhibitors Review articles on Phosphodiesterase inhibitors Articles on Phosphodiesterase inhibitors in N Eng J Med, Lancet, BMJ Media Powerpoint slides on Phosphodiesterase inhibitors Images of Phosphodiesterase inhibitors Photos ... [88%] 2023-12-20 [Phosphodiesterase inhibitors] [Drugs]...
8. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Chemistry) [88%] 2023-12-15 [Enzyme inhibitors]
9. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. (Chemistry) [88%] 2023-12-16 [Tyrosine kinase inhibitors]
10. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. [88%] 2023-12-20 [Tyrosine kinase inhibitors]
11. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Drug class) [88%] 2024-09-01 [Enzyme inhibitors]
12. Inhibitory control: Inhibitory control, also known as response inhibition, is a cognitive process – and, more specifically, an executive function – that permits an individual to inhibit their impulses and natural, habitual, or dominant behavioral responses to stimuli (a.k.a. prepotent responses) in ... (Philosophy) [79%] 2023-07-04 [Cognition] [Attention deficit hyperactivity disorder]...
13. Enzyme inhibitor: Editor-In-Chief: C. Michael Gibson, M.S., M.D. [78%] 2023-08-07 [Medicinal chemistry] [Enzymes]...
14. PDE3 inhibitor: A PDE3 inhibitor is a drug which inhibits the action of the phosphodiesterase enzyme PDE3. They are used for the therapy of acute heart failure and cardiogenic shock. [78%] 2023-02-24 [PDE3 inhibitors]
15. Aromatase inhibitor: Aromatase inhibitors, which inhibit the enzyme aromatase used biologically to produce estrogens, inhibit the biosynthetic production of estrogen steroids. Because of this action, these inhibitors are sometimes used to treat cancerous tumors, which are estrogen-sensitive, especially breast cancer in ... [78%] 2023-08-09
16. Reaction inhibitor: A reaction inhibitor is a substance that decreases the rate of, or prevents, a chemical reaction. A catalyst, in contrast, is a substance that increases the rate of a chemical reaction. (Chemistry) [78%] 2022-03-01 [Catalysis]
17. Fusion inhibitor: A fusion inhibitor is a class of antiretroviral drugs used to treat viral infections such as HIV. It works by blocking the virus from fusing with a cell's membrane to enter and infect the cell. [78%] 2023-03-25 [Antiretroviral drugs]
18. PDE5 inhibitor: A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues ... (Vasodilating drug) [78%] 2023-08-13 [PDE5 inhibitors]
19. Cholinesterase inhibitor: Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or butyrylcholine. This increases the amount of the acetylcholine or butyrylcholine in the synaptic cleft that can bind to muscarinic receptors, nicotinic ... (Chemicals which prevent breakdown of acetylcholine and butyrylcholine) [78%] 2023-11-19 [Neurophysiology] [Neurotoxins]...
20. Protease inhibitor: A protease inhibitor is a chemical compound that inhibits the functions of proteases to control viral infections, especially so for the treatment of HIV/AIDS and hepatitis C, but also for the treatment of other viruses, such as chicken pox ... [78%] 2022-03-06