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1. Discovery and development of neuraminidase inhibitors: Neuraminidase inhibitors inhibit enzymatic activity of the enzyme neuraminidase (sialidase). These type of inhibitors have been introduced as anti-influenza drugs as they prevent the virus from exiting infected cells and thus stop further spreading of the virus. [100%] 2023-04-20 [Drug discovery] [Neuraminidase inhibitors]...

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1. Neuraminidase: Neuraminidase enzymes are glycoside hydrolase enzymes that cleave (cut) the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. [100%] 2023-03-23 [Carbohydrate chemistry] [EC 3.2.1]...
2. Viral neuraminidase: Viral neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell. Neuraminidases are enzymes that cleave sialic acid (also called neuraminic acid) groups from glycoproteins. [70%] 2023-08-20 [Viral enzymes] [Influenza A virus]...
3. Hemagglutinin-neuraminidase: Hemagglutinin-neuraminidase refers to a single viral protein that has both hemagglutinin and (endo) neuraminidase EC 3.2.1.18 activity. This is in contrast to the proteins found in influenza, where both functions exist but in two separate proteins. [70%] 2023-04-15 [EC 3.2.1] [GH family]...
4. Inheritors (play): Inheritors is a four-act play written by the American dramatist Susan Glaspell, first performed in 1921 (103 years ago) (1921). The play concerns the legacy of an idealistic farmer who wills his highly coveted midwest farmland to the establishment ... (Play) [61%] 2024-01-01 [1921 plays] [Plays by Susan Glaspell]...
5. Parainfluenza hemagglutinin-neuraminidase: Parainfluenza hemagglutinin-neuraminidase is a type of hemagglutinin-neuraminidase produced by parainfluenza. (Type of hemagglutinin-neuraminidase) [57%] 2022-11-19 [Viral structural proteins]
6. PCSK9 inhibitors: PCSK9 inhibitors are a class of medications used to treat hypercholesterolemia. In those on high doses of statins, they decrease risk of further problems by 1.5% over 2.5 years. [54%] 2024-01-01
7. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... (Chemistry) [54%] 2023-12-17 [Protein kinase inhibitors]
8. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... [54%] 2024-02-11 [Protein kinase inhibitors]
9. Lipase inhibitors: Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. [54%] 2023-12-19 [Lipase inhibitors] [Obesity]...
10. Protease inhibitors: Protease inhibitors (PIs) are a class of medication used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 protease, an enzyme used by the viruses to ... [54%] 2023-10-09 [Antivirals] [Antiretroviral drugs]...
11. Phosphodiesterase inhibitors: Articles Most recent articles on Phosphodiesterase inhibitors Most cited articles on Phosphodiesterase inhibitors Review articles on Phosphodiesterase inhibitors Articles on Phosphodiesterase inhibitors in N Eng J Med, Lancet, BMJ Media Powerpoint slides on Phosphodiesterase inhibitors Images of Phosphodiesterase inhibitors Photos ... [54%] 2023-12-20 [Phosphodiesterase inhibitors] [Drugs]...
12. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Chemistry) [54%] 2023-12-15 [Enzyme inhibitors]
13. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. (Chemistry) [54%] 2023-12-16 [Tyrosine kinase inhibitors]
14. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. [54%] 2023-12-20 [Tyrosine kinase inhibitors]
15. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Drug class) [54%] 2024-09-01 [Enzyme inhibitors]
16. Inhibitory control: Inhibitory control, also known as response inhibition, is a cognitive process – and, more specifically, an executive function – that permits an individual to inhibit their impulses and natural, habitual, or dominant behavioral responses to stimuli (a.k.a. prepotent responses) in ... (Philosophy) [48%] 2023-07-04 [Cognition] [Attention deficit hyperactivity disorder]...
17. Enzyme inhibitor: Editor-In-Chief: C. Michael Gibson, M.S., M.D. [48%] 2023-08-07 [Medicinal chemistry] [Enzymes]...
18. PDE3 inhibitor: A PDE3 inhibitor is a drug which inhibits the action of the phosphodiesterase enzyme PDE3. They are used for the therapy of acute heart failure and cardiogenic shock. [48%] 2023-02-24 [PDE3 inhibitors]
19. Aromatase inhibitor: Aromatase inhibitors, which inhibit the enzyme aromatase used biologically to produce estrogens, inhibit the biosynthetic production of estrogen steroids. Because of this action, these inhibitors are sometimes used to treat cancerous tumors, which are estrogen-sensitive, especially breast cancer in ... [48%] 2023-08-09