Phenylpiperazine

Phenylpiperazine
Names
	Preferred IUPAC name 1-Phenylpiperazine
Identifiers
CAS Number	92-54-6 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL9434 ;
ChemSpider	6829 ;
PubChem CID	7096;
UNII	J9225CBI7D ;
	InChI InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 Key: YZTJYBJCZXZGCT-UHFFFAOYSA-N ;
	SMILES c1cc(ccc1)N2CCNCC2;
Properties
Chemical formula	C10H14N2
Molar mass	162.23 g/mol
Appearance	clear colourless to yellow liquid
Density	1.028g/cm3
Melting point	18.8 °C (65.8 °F; 291.9 K)
Boiling point	287.2 °C (549.0 °F; 560.3 K) at 760mmHg
Solubility in water	insoluble
Hazards
Flash point	138.3 °C (280.9 °F; 411.4 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.^[1]

1-Phenylpiperazine is toxic, its oral LD50 in rats is 210 mg/kg.^[2]

List phenylpiperazine derivatives

Alpertine [27076-46-6]
BP 554 [82900-57-0]
Butropipazone [2354-61-2]
CAM89 alluded to here: WO patent 2018102233
Centphenaquin [98459-16-6]
Centpropazine [91315-34-3] [34675-77-9]
Clodoxopone [71923-34-7]
Dropropizine [17692-31-8]
Etoperidone
FAUC-299 [313972-96-2]
FAUC-312 [562104-72-7]
LASSBio-579 [591774-47-9]
LASSBio-581 [591774-48-0]
LASSBio-632
LASSBio-680
LASSBio-724
LASSBio-729 [66307-58-2]
LASSBio-730
McN 261 [1044-59-3]
Nefazodone
Niaprazine
Oxypertine
PD-158771 [189152-50-9]
PO-219
Trazodone
WIN 18,437 [4121-77-1]

References

↑ World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances". https://www.who.int/medicines/services/inn/RevisedFinalStemBook2006.pdf.
↑ "1-Phenylpiperazine". https://pubchem.ncbi.nlm.nih.gov/compound/7096#section=Toxicity&fullscreen=true.

External links

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Original source: https://en.wikipedia.org/wiki/Phenylpiperazine. Read more

[The_use_of_stems_in_the_selection_of_International_Nonproprietary_Names_(INN)_for_pharmaceutical_substances-1] World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances". https://www.who.int/medicines/services/inn/RevisedFinalStemBook2006.pdf.

[2] "1-Phenylpiperazine". https://pubchem.ncbi.nlm.nih.gov/compound/7096#section=Toxicity&fullscreen=true.

v t e Piperazines
Simple piperazines (no additional rings)	1-Cyclohexylpiperazine Aminoethylpiperazine Diethylcarbamazine HEPPS Midafotel Piperazine PIPES
Phenylpiperazines	Acaprazine Antrafenine Aripiprazole Batoprazine Bifeprunox BRL-15,572 Ciprofloxacin CSP-2503 Dapiprazole DCPP DMPP Diphenylpiperazine Dropropizine EGIS-12,233 Elopiprazole Eltoprazine Enpiprazole Ensaculin Etoperidone Flesinoxan Fluanisone Flibanserin Fluprazine Itraconazole Ketoconazole Levodropropizine Lorpiprazole mCPP Mefway MeOPP Mepiprazole Naftopidil Naluzotan Naphthylpiperazine Nefazodone Niaprazine Oxypertine Pardoprunox pCPP pFPP Posaconazole S-14,506 S-14,671 S-15,535 SB-258,585 SB-271,046 SB-357,134 SB-399,885 Sonepiprazole TFMPP Tolpiprazole Trazodone Urapidil Vesnarinone Vilazodone Vortioxetine WAY-100,135 WAY-100,635
Benzylpiperazines	2C-B-BZP Befuraline Bifeprunox Buclizine BZP Chlorbenzoxamine DBZP Fipexide Imatinib MBZP MDBZP Meclozine Methoxypiperamide Piberaline Piribedil Sunifiram Trimetazidine Vesnarinone
Diphenylalkylpiperazines (benzhydrylalkylpiperazines)	AD-1211 Almitrine Amperozide BRL-15,572 Buclizine BW373U86 Cetirizine Chlorbenzoxamine Chlorcyclizine Cinnarizine Clocinizine Cyclizine DBL-583 Diphenpipenol Diphenylmethylpiperazine Dotarizine DPI-221 DPI-287 DPI-3290 GBR-12,783 GBR-12,935 GBR-13,069 GBR-13,098 GBR-13,119 Hydroxyzine Lidoflazine Manidipine Meclozine MT-45 Oxatomide SNC-80 Vanoxerine
Pyrimidinylpiperazines	Buspirone Dasatinib Eptapirone Gepirone Ipsapirone Piribedil Prazitone Pyrimidinylpiperazine Revospirone Tandospirone Tirilazad Trimazosin Umespirone Zalospirone
Pyridinylpiperazines	Atevirdine Azaperone Delavirdine Mirtazapine Pyridinylpiperazine
Benzo(iso)thiazolylpiperazines	Lurasidone Perospirone Revospirone Tiospirone Ziprasidone
Tricyclics (piperazine attached via side chain)	Amoxapine Clopenthixol Clorotepine Clozapine Cyanothepin Doclothepin Docloxythepin Flupentixol Fluphenazine Isofloxythepin Loxapine Meperathiepin Metitepine Octomethothepin Olanzapine Opipramol Oxyclothepin Oxyprothepin Peradithiepin Perathiepin Perazine Perphenazine Pirenzepine Prochlorperazine Thiethylperazine Thiothixene Trifluoperazine Trifluthepin Zuclopenthixol
Others/Uncategorized	6-Nitroquipazine Azimilide Cinepazet Cinepazic acid Cinepazide Cyclohexylpiperazine EGIS-7625 Hexocyclium Indinavir JNJ-7777120 Lodenafil Mirodenafil PB-28 Quipazine Ranolazine SA-4503 Sildenafil Tadalafil Vardenafil VUF-6002 WY-46824 Zipeprol

Phenylpiperazine

Contents

List phenylpiperazine derivatives

See also

References

External links