Acetic Acid (Medical Use)

Acetic acid
	Chemical formula of acetic acid
Clinical data
Pronunciation	a-SEE-tik
Trade names	Acetasol, Vasotate, Domeboro Otic, others
Other names	Vinegar
AHFS/Drugs.com	Monograph
License data	US DailyMed: Acetic_acid;
Routes of; administration	ear drops, irrigation, by mouth
ATC code	S02AA10 (WHO) ;
Legal status
Legal status	US: ℞-only / OTC;
Identifiers
	IUPAC name acetic acid;
CAS Number	64-19-7;
PubChem CID	176;
DrugBank	DB03166;
ChemSpider	171;
UNII	Q40Q9N063P;
KEGG	D00010; C00033;
ChEBI	CHEBI:15366;
ChEMBL	ChEMBL539;
PDB ligand	ACY (PDBe, RCSB PDB);
Chemical and physical data
Formula	C2H4O2
Molar mass	60.052 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)O;
	InChI InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4); Key:QTBSBXVTEAMEQO-UHFFFAOYSA-N;

Acetic acid, which at low concentrations is known as vinegar, is an acid used to treat a number of conditions.

Definition and medical uses

As an eardrop it is used to treat infections of the ear canal.^[1] It may be used with an ear wick.^[2] As a liquid it is used to flush the bladder in those who have a urinary catheter in an attempt to prevent infection or blockage.^[3] As a gel it may be used to adjust the pH of the vagina.^[4] It may also be applied to the cervix to help detect cervical cancer during screening.^[5]

Side effects may include burning at the site of application.^[6] Allergic reactions may rarely occur.^[6] Use is not recommended in the ear in people who have a hole in the eardrum.^[7] It works against both bacterial and fungal causes of external ear infections.^[7]

History and culture

Acetic acid has been used medically since the time of Ancient Egypt.^[8]^[9] It is on the World Health Organization's List of Essential Medicines.^[10] Acetic acid is more commonly used for external ear infections in the developing world than the developed.^[11]

References

↑ "Acetic acid (otic) medical facts from Drugs.com". Archived from the original on 18 January 2017. https://web.archive.org/web/20170118041716/https://www.drugs.com/mtm/acetic-acid-otic.html. Retrieved 14 January 2017.
↑ Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 252. ISBN 9781284057560.
↑ "Acetic Acid". The American Society of Health-System Pharmacists. Archived from the original on 18 January 2017. https://web.archive.org/web/20170118041827/https://www.drugs.com/monograph/acetic-acid.html. Retrieved 8 January 2017.
↑ "Acetic acid gel: Indications, Side Effects, Warnings - Drugs.com". Archived from the original on 18 January 2017. https://web.archive.org/web/20170118041818/https://www.drugs.com/cdi/acetic-acid-gel.html. Retrieved 14 January 2017.
↑ Fokom-Domgue, J; Combescure, C; Fokom-Defo, V; Tebeu, PM; Vassilakos, P; Kengne, AP; Petignat, P (3 July 2015). "Performance of alternative strategies for primary cervical cancer screening in sub-Saharan Africa: systematic review and meta-analysis of diagnostic test accuracy studies.". BMJ (Clinical Research Ed.) 351: h3084. doi:10.1136/bmj.h3084. PMID 26142020.
↑ ^6.0 ^6.1 "Acetic acid otic Side Effects in Detail - Drugs.com". Archived from the original on 18 January 2017. https://web.archive.org/web/20170118041810/https://www.drugs.com/sfx/acetic-acid-otic-side-effects.html. Retrieved 14 January 2017.
↑ ^7.0 ^7.1 "Acetic Acid - FDA prescribing information, side effects and uses". Archived from the original on 18 January 2017. https://web.archive.org/web/20170118041704/https://www.drugs.com/pro/acetic-acid.html. Retrieved 14 January 2017.
↑ Cook, Larry (2005) (in en). The Beginner's Guide to Natural Living: How to Cultivate a More Natural Lifestyle to Lose Weight, Prevent Degenerative Disease, Improve Your Energy and Attain Vibrant Health. EcoVision Communications. p. 107. ISBN 9780975536186. https://books.google.com/books?id=9_h08MyyjVMC&pg=PA107.
↑ Cumston, C. G. (2013) (in en). The History of Medicine. Routledge. p. Chapter 2. ISBN 9781136194252. https://books.google.com/books?id=Obb7AQAAQBAJ&pg=PT69.
↑ World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. 2019. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
↑ Desai, Bobby; Desai, Alpa (2016) (in en). Primary Care for Emergency Physicians. Springer. p. 36. ISBN 9783319443607. https://books.google.com/books?id=1DOgDQAAQBAJ&pg=PA36.