Poly(Adp-Ribose) Polymerase Family Member 14

Short description: Protein-coding gene in the species Homo sapiens

Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene. ^[1]

Function

Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).

References

↑ "Entrez Gene: Poly(ADP-ribose) polymerase family member 14". https://www.ncbi.nlm.nih.gov/gene/54625. Retrieved 2016-03-02.

v t e DNA repair
Excision repair	Base excision repair/AP site DNA glycosylase Uracil-DNA glycosylase Poly ADP ribose polymerase Nucleotide excision repair/ERCC XPA XPB XPC XPD/ERCC2 XPE/DDB1 XPF/DDB1 XPG/ERCC5 ERCC1 RPA RAD23A RAD23B Excinuclease DNA mismatch repair MLH1 MSH2
Other forms of repair	Transcription-coupled repair ERCC6 ERCC8 Homology directed repair Non-homologous end joining Ku Microhomology-mediated end joining Postreplication repair Photolyase CRY1 CRY2
Other/ungrouped proteins	Ogt PcrA Proliferating Cell Nuclear Antigen Homologous recombination RecA/RAD51 Sgs1 Slx4
Regulation	SOS box SOS response
Other/ungrouped	8-Oxoguanine Adaptive response Meiotic recombination checkpoint RecF pathway DNA helicase: BLM WRN FANC proteins: core protein complex FANCA FANCB FANCC FANCE FANCF FANCG FANCL FANCM FANCD1 FANCD2 FANCI FANCJ FANCN

Poly(Adp-Ribose) Polymerase Family Member 14

Function

References

Further reading