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1. Цитохром P450: Цитохром P450 (цитохром P450-зависимая монооксигеназа, англ. cytochrome P450, CYP) — общее название ферментов семейства P450. [100%] 2023-09-16
2. Cytochrome P450: Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of ... (Biology) [100%] 2024-01-12 [Cytochrome P450] [EC 1.14]...
3. Citocromo P450: El citocromo P450 (abreviado CYP en inglés, o CIP en español, o simplemente P450) es una enorme y diversa superfamilia de hemoproteínas encontradas en bacterias, archaea y eucariotas.​ Las proteínas del citocromo P450 usan un amplio rango de compuestos exógenos ... [100%] 2024-01-11
4. Cytochrome P450: Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of ... (Class of enzymes) [100%] 2024-01-11 [Cytochrome P450] [EC 1.14]...
5. P50 (pressure): In biochemistry, p50 represents the partial pressure of a gas required to achieve 50% saturation of a particular protein's binding sites. Values of p50 are negatively correlated with substrate affinity; lower values correspond to higher affinity and vice versa. (Physics) [94%] 2024-01-07 [Enzyme kinetics] [Units of pressure]...
6. Inheritors (play): Inheritors is a four-act play written by the American dramatist Susan Glaspell, first performed in 1921 (103 years ago) (1921). The play concerns the legacy of an idealistic farmer who wills his highly coveted midwest farmland to the establishment ... (Play) [93%] 2024-01-01 [1921 plays] [Plays by Susan Glaspell]...
7. PCSK9 inhibitors: PCSK9 inhibitors are a class of medications used to treat hypercholesterolemia. In those on high doses of statins, they decrease risk of further problems by 1.5% over 2.5 years. [83%] 2024-01-01
8. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... (Chemistry) [83%] 2023-12-17 [Protein kinase inhibitors]
9. PERK inhibitors: A PERK inhibitor is a small molecule compound that unlike any existing drug inhibits the expression of protein kinase RNA–like endoplasmic reticulum kinase. The (first such) inhibitor demonstrated the ability to halt brain cell death in mice with prion ... [83%] 2024-02-11 [Protein kinase inhibitors]
10. Lipase inhibitors: Lipase inhibitors are substances used to reduce the activity of lipases found in the intestine. Lipases are secreted by the pancreas when fat is present. [83%] 2023-12-19 [Lipase inhibitors] [Obesity]...
11. Protease inhibitors: Protease inhibitors (PIs) are a class of medication used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of HIV-1 protease, an enzyme used by the viruses to ... [83%] 2023-10-09 [Antivirals] [Antiretroviral drugs]...
12. Phosphodiesterase inhibitors: Articles Most recent articles on Phosphodiesterase inhibitors Most cited articles on Phosphodiesterase inhibitors Review articles on Phosphodiesterase inhibitors Articles on Phosphodiesterase inhibitors in N Eng J Med, Lancet, BMJ Media Powerpoint slides on Phosphodiesterase inhibitors Images of Phosphodiesterase inhibitors Photos ... [83%] 2023-12-20 [Phosphodiesterase inhibitors] [Drugs]...
13. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Chemistry) [83%] 2023-12-15 [Enzyme inhibitors]
14. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. (Chemistry) [83%] 2023-12-16 [Tyrosine kinase inhibitors]
15. Angiokinase inhibitors: Angiokinase inhibitors are a new therapeutic target for the management of cancer. They inhibit tumour angiogenesis, one of the key processes leading to invasion and metastasis of solid tumours, by targeting receptor tyrosine kinases. [83%] 2023-12-20 [Tyrosine kinase inhibitors]
16. STAT inhibitors: STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors of STAT proteins are being developed for use in cancer therapy. (Drug class) [83%] 2024-09-01 [Enzyme inhibitors]
17. Cytochrom P450 27B1: Das Cytochrome P450, Familie 27, Subfamilie B, Polypeptid 1 (kurz: CYP27B1 oder herkömmlich: 1α-Hydroxylase) ist ein Mitglied der Cytochrom P450-Enzym-Superfamilie. Es hydroxyliert das Prohormon 25(OH)Vitamin D3 zu 1,25(OH)2Vitamin D3 und aktiviert es so. [81%] 2024-01-19
18. Cytochrome P450 cam: Cytochrome P450 camphor 5-monooxygenase is a bacterial enzyme originally from Pseudomonas putida, which catalyzes a critical step in the metabolism of camphor. In 1987, Cytochrome P450cam was the first cytochrome P450 three-dimensional protein structure solved by X-ray ... (Biology) [81%] 2024-01-12 [Cytochrome P450] [EC 1.14.15]...
19. Cytochrome P450 eryF: 6-deoxyerythronolide B hydroxylase is an Actinomycetota Cytochrome P450 enzyme originally from Saccharopolyspora erythraea, catalyzes the 6S-hydroxylate of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) which is the first step of biosynthesis of the macrolide antibiotic erythromycin ... (Enzyme) [81%] 2024-01-11 [Cytochrome P450] [EC 1.14.15]...
20. Cytochrom P450 1A2: Cytochrom P450 1A2 (CYP1A2) ist ein Hämprotein-Enzym aus der Cytochrom-P450-Gruppe. Das Protein verstoffwechselt Östrogene und verschiedene Xenobiotika, darunter Koffein, durch eine Oxidation bzw. [81%] 2024-01-12