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Selective glucocorticoid receptor modulator: Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical ... (Chemistry) [100%] 2023-12-19 [Anti-inflammatory agents] [Immunosuppressants]...
Selective glucocorticoid receptor modulator: Selective glucocorticoid receptor modulators (SEGRMs) and selective glucocorticoid receptor agonists (SEGRAs) formerly known as dissociated glucocorticoid receptor agonists (DIGRAs) are a class of experimental drugs designed to share many of the desirable anti-inflammatory, immunosuppressive, or anticancer properties of classical ... (Class of experimental drugs) [100%] 2023-12-19 [Anti-inflammatory agents] [Immunosuppressants]...
Glucocorticoid receptor: The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and ... (Receptor to which cortisol and other glucocorticoids bind) [95%] 2023-05-31 [Genome projects] [Nuclear receptors]...
Glucocorticoid receptor: Glucocorticoid receptors are intracellular proteins to which drugs of the glucocorticoid class bind and cause physiologic affects. They are related to mineralocorticoid receptors and less so to androgen receptors and estrogen receptors. [95%] 2023-07-25
Glucocorticoid: Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. (Chemistry) [79%] 2022-11-28 [Chemical substances for emergency medicine] [Corticosteroids]...
Glucocorticoid: Glucocorticoids are defined as "a group of corticosteroids that affect carbohydrate metabolism (gluconeogenesis, liver glycogen deposition, elevation of blood sugar), inhibit adrenocorticotropic hormone secretion, and possess pronounced anti-inflammatory activity. These steroids also play a role in fat and protein ... [79%] 2023-02-04
Glucocorticoide: Los glucocorticoides son hormonas de la familia de los corticosteroides que participan en la regulación del metabolismo de carbohidratos favoreciendo la gluconeogénesis y la glucogenólisis; poseen además actividad inmunosupresora. Su acción reguladora se extiende también al metabolismo intermedio de grasas ... [73%] 2024-06-16
Selective receptor modulator: In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues. A SRM may behave as an agonist in some tissues while as an antagonist in others. (Chemistry) [69%] 2023-12-20 [Pharmacodynamics]
Selective receptor modulator: In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues. A SRM may behave as an agonist in some tissues while as an antagonist in others. [69%] 2024-06-17 [Pharmacodynamics]
Selective progesterone receptor modulator: Articles Most recent articles on Selective progesterone receptor modulator Most cited articles on Selective progesterone receptor modulator Review articles on Selective progesterone receptor modulator Articles on Selective progesterone receptor modulator in N Eng J Med, Lancet, BMJ Media Powerpoint slides ... [60%] 2023-12-20 [hormonal agents] [Endocrinology]...
Selective estrogen receptor modulator: Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonist/antagonists (ERAAs), are a class of drugs that act on the estrogen receptor (ER). A characteristic that distinguishes these substances from pure ER agonists and antagonists (that is, full ... (Chemistry) [60%] 2023-10-24 [Selective estrogen receptor modulators]
Selective androgen receptor modulator: Selective Androgen Receptor Modulators or SARMs are a class of androgen receptor ligands that were developed with the intention of maintaining some of the desirable effects of androgens, such as preventing osteoporosis and muscle loss while reducing risks of undesirable ... (Chemistry) [60%] 2024-01-07 [Selective androgen receptor modulators]
Selective androgen receptor modulator: Selective androgen receptor modulators (SARMs) are a class of drugs that selectively act on the androgen receptor in the muscle and bone. Non-selective anabolic androgenic steroids (AAS) are potentially useful for a variety of medical conditions, but their use ... (Class of pharmaceutical drugs) [60%] 2023-12-27 [Selective androgen receptor modulators]
Receptor (comunicación): Receptor, es el agente (persona o equipo) que recibe el mensaje, señal o código emitido por un emisor, transmisor o enunciante; es el destinatario que recibe la información. El receptor realiza un proceso inverso al del emisor, ya que descifra ... (Comunicación) [56%] 2024-04-24
Receptor (biochemistry): In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems. These signals are typically chemical messengers which bind to a receptor and produce physiological responses such as ... (Biochemistry) [56%] 2024-06-25 [Receptors] [Cell biology]...
Sphingosine-1-phosphate receptor modulator: Sphingosine-1-phosphate receptor modulators are a class of drugs used as immunomodulators, most notably in cases of multiple sclerosis. These drugs have the ability to modulate the G-protein coupled S1P receptors. (Drug class) [54%] 2024-01-01 [Multiple sclerosis] [S1P receptor modulators]...
AMPA receptor positive allosteric modulator: AMPA receptor positive allosteric modulators are positive allosteric modulators (PAMs) of the AMPA receptor (AMPR), a type of ionotropic glutamate receptor which mediates most fast synaptic neurotransmission in the central nervous system. AMPAR PAMs have cognition- and memory-enhancing and ... (Chemistry) [54%] 2023-12-19 [AMPA receptor positive allosteric modulators]
AMPA receptor positive allosteric modulator: AMPA receptor positive allosteric modulators are positive allosteric modulators (PAMs) of the AMPA receptor (AMPR), a type of ionotropic glutamate receptor which mediates most fast synaptic neurotransmission in the central nervous system. AMPAR PAMs have cognition- and memory-enhancing and ... [54%] 2023-12-19 [AMPA receptor positive allosteric modulators]